Protein Alignment Stacl and STAC

DIOPT Version :9

• Sequence 1: NP_001260996.1
• Gene: Stacl / 5740318
• FlyBaseID: FBgn0263980
• Length: 1970
• Species: Drosophila melanogaster
• Sequence 2: XP_024309490.1
• Gene: STAC / 6769
• HGNCID: 11353
• Length: 406
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 127/590 - (21%)
• Similarity: 207/590 - (35%)
• Gaps: 217/590 - (36%)

  Fly   586 QLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSP 650
            :::::..|||      .:|.:: ::.:|:..||.|...||:|         ..|.|..:......
Human    25 KIEEASHALN------YQGNIF-QLQKLKRSLSFKTKSLRSK---------SADNFFQRTNSEDM 73

  Fly   651 RNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADSQPPRQNQMYHAVSTVLTLRRNGASSTA 715
            :.:....|..:||         .|..||                                ..|..
Human    74 KLQAHMVAEISPS---------SSPLPA--------------------------------PGSLT 97

  Fly   716 SEPLRPNL---DGSHHLQEYTYKKITACDVCSQILRG-HTRQGLRCRICKLNAHGDCAPNL--PR 774
            |.|.|..|   ..:|..|||.:||.|.||||:.::.| :.:.||||:.||::.|..|...|  .|
Human    98 STPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQR 162

  Fly   775 CQPK-QKLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPP 838
            |..| .|..||..|:..|     |.|:.|..|.|.      .:|.|:.:. ||......|
Human   163 CMGKLPKGFRRYYSSPLL-----IHEQFGCIKEVM------PIACGNKVD-PVYETLRFG----- 210

  Fly   839 DIPIVSVSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQ 903
                                             .|:||    |..:|
Human   211 ---------------------------------TSLAQ----RTKKG------------------ 220

  Fly   904 ELQQQRGGLPVPSQDISSSSAPHSPRRQKLNLRMKSLSLDSPESSELHGQFRRRTQLPGTGASTS 968
                            ||.|...||.|..     .|..::.||.:
Human   221 ----------------SSGSGSDSPHRTS-----TSDLVEVPEEA-------------------- 244

  Fly   969 AGSGYYHGGSGGHLEHSTPPSNNSRLHSPSSPSHPGRKLLYATRGMRGGSVDLPDEME--KSQSS 1031
                  :|..||:         :.|..|.|..::|           ..|:.|..|..:  ..|.|
Human   245 ------NGPGGGY---------DLRKRSNSVFTYP-----------ENGTDDFRDPAKNINHQGS 283

  Fly  1032 ASTSPCLSPKTHRLLPTNLYVIIYNFKARHADELDLKAGYKVTVIDNSDPDWWKGKVLGRVGYFP 1096
            .|..|         |..|.||.:|.|..:..::|:::.|..:|::::|:.||||||:..|:|:||
Human   284 LSKDP---------LQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFP 339

  Fly  1097 SKYCVRLNANEKPLQVTHNLQVSDSERGENLTLLRDQIVIQTGDEVNGMVMIRAAEHGQGYCPIK 1161
            :.:..||..|||..:..... :...|:|: :||..:||.:.:.:|.:|.:.:.:.:. :|..|:.
Human   340 ANFVQRLQQNEKIFRCVRTF-IGCKEQGQ-ITLKENQICVSSEEEQDGFIRVLSGKK-KGLIPLD 401

  Fly  1162 YLQEV 1166
            .|:.:
Human   402 VLENI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stacl	NP_001260996.1	BAR	290..489	CDD:299863
		C1	727..773	CDD:237996	21/48 (44%)
		SH3	1051..1102	CDD:302595	18/50 (36%)
STAC	XP_024309490.1	C1	112..163	CDD:237996	21/50 (42%)
		STAC2_u1	170..>241	CDD:318801	26/163 (16%)
		SH3_Stac_1	293..345	CDD:212767	18/51 (35%)
		SH3_Stac_2	352..402	CDD:212768	10/52 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10868
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41179
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15135
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1389
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.010