DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stacl and Stac2

DIOPT Version :9

Sequence 1:	NP_001260996.1	Gene:	Stacl / 5740318	FlyBaseID:	FBgn0263980	Length:	1970	Species:	Drosophila melanogaster
Sequence 2:	XP_038942431.1	Gene:	Stac2 / 363674	RGDID:	1305548	Length:	439	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	99/465 - (21%)
Similarity:	166/465 - (35%)	Gaps:	145/465 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 PLRP-NLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNL--PRCQPKQ 779
            ||:| .|   |..||:.:|:.:.|::|.|::.|:::|||||:.||::.|..|:..:  .:|..|.
  Rat   104 PLKPVRL---HSFQEHVFKRASPCELCHQLIVGNSKQGLRCKTCKVSVHLWCSEEISHQQCPGKT 165

  Fly   780 KLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPPDIPIVS 844
            ....|:..:|.|                                        |...|||
  Rat   166 STSFRRNFSSPL----------------------------------------LVHEPPP------ 184

  Fly   845 VSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQELQQQR 909
                                       |......:...|...:..||             .:..|
  Rat   185 ---------------------------ACAMSKESPPTGTSGKVDPV-------------YETLR 209

  Fly   910 GGLPVPSQDISS-SSAPHSPRRQKLNLRMKSLSLDSPESSELHGQFRRRTQLPGTGAST----SA 969
            .|..:...:.|| ||...||.|        |||.....:.:..|..|...:.||....|    |.
  Rat   210 YGTSLALMNRSSFSSTSESPTR--------SLSERDELTEDGEGSIRSSEEGPGDSVFTAPVESE 266

  Fly   970 GSGYYHGGSGGHLEHSTPPSNNSRLHSPSSPSHPGRKLLYATRGMRGGSVDLPDEMEKSQSSAST 1034
            |||         .|..:|....           ||..:...::...||:.:.|         ..|
  Rat   267 GSG---------AEEKSPGQQT-----------PGASMHIHSKWTMGGARNWP---------TIT 302

  Fly  1035 SPCL------SPKTHRLLPTNLYVIIYNFKARHADELDLKAGYKVTVIDNSDPDWWKGKVLGRVG 1093
            .|.|      .|....:.|...||.:|.|..:..::|.|:.|.::.::|:|:.||||||:..|||
  Rat   303 DPELFLQPPKLPVRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVG 367

  Fly  1094 YFPSKYCVRLNANEKPLQVTHNLQVSDSERGENLTLLRDQIV--IQTGDEVNGMVMIRAAEHGQG 1156
            :||:.:..|:...|...:...... .:.|:| .::|..:||.  :....:.:|.:.:.:.:. :|
  Rat   368 FFPANFVQRVRPGENVWRCCQPFS-GNKEQG-YMSLKENQICVGVSRSKDSDGFIRVSSGKK-RG 429

  Fly  1157 YCPIKYLQEV 1166
            ..|:..|.|:
  Rat   430 LVPVDSLAEI 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stacl	NP_001260996.1	BAR	290..489	CDD:299863
		C1	727..773	CDD:237996	17/47 (36%)
		SH3	1051..1102	CDD:302595	20/50 (40%)
Stac2	XP_038942431.1	C1_Stac2	106..164	CDD:410431	20/60 (33%)
		STAC2_u1	167..323	CDD:406951	44/278 (16%)
		SH3_Stac2_C	324..376	CDD:212918	20/51 (39%)
		SH3	383..434	CDD:418401	8/53 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10604
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45320
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15135
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1389
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010