DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nox and FRO3

DIOPT Version :9

Sequence 1:	NP_001097336.1	Gene:	Nox / 5740310	FlyBaseID:	FBgn0085428	Length:	1340	Species:	Drosophila melanogaster
Sequence 2:	NP_001185067.1	Gene:	FRO3 / 838910	AraportID:	AT1G23020	Length:	717	Species:	Arabidopsis thaliana

Alignment Length:	358	Identity:	88/358 - (24%)
Similarity:	151/358 - (42%)	Gaps:	72/358 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 ITVNLCLFISRAIQYRASNGFVIIARACGQCLNFNCAWVLVLMLRHSLTYLRGRGLSSYLPLDHH 594
            :|.|:||            ||:....|.|..|                  |...||:|.....:|
plant   199 LTGNICL------------GFLFYPVARGSSL------------------LAAVGLTSESSTKYH 233

  Fly   595 VYLHKLTGITISVLSLIHTIMHLFNFSIIVINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPT 659
            ::|..|      |::|..:  |...:.|..|:...::    .:.||   ||.|:..|       .
plant   234 IWLGNL------VMTLFTS--HGLCYCIYWISTNQVS----QMLEW---DRTGISHL-------A 276

  Fly   660 GVALLAILVVMFVCSQPFVRRKGSFEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGL-VYIVER 723
            |...|...::|:..:.|.:||: .||||::||.||:.|.:..:||....:.....||. :::|:|
plant   277 GEIALVAGLLMWATTFPAIRRR-FFEVFFYTHYLYMVFMLFFVFHVGISYALISFPGFYIFMVDR 340

  Fly   724 ALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEWHPFTISSA 788
            .|||:..|   ....:.|..:||.:.|.|...:.....:.|...:|||||:|:..:||||||:|:
plant   341 FLRFLQSR---NNVKLVSARVLPCETVELNFSKNPMLMYSPTSILFVNIPSISKLQWHPFTITSS 402

  Fly   789 PEQE-DYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTP----SFMLLNEAR 848
            .:.| ..:.:.|::.|:|:::|:...          .||.:|.....::..|    |...|....
plant   403 SKLEPKKLSVMIKSQGKWSSKLHHML----------ASSNQIDHLAVSVEGPYGPASTDYLRHDS 457

  Fly   849 NPAIAGERSATPQTDFLAKNLGVQAVPPVRPPR 881
            ...::|....||....:...|.|.:....:.|:
plant   458 LVMVSGGSGITPFISIIRDLLYVSSTNAYKTPK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nox	NP_001097336.1	FRQ1	314..466	CDD:227455
		EFh	365..425	CDD:238008
		EFh	399..462	CDD:238008
		Ferric_reduct	560..700	CDD:280043	34/139 (24%)
		NOX_Duox_like_FAD_NADP	744..>819	CDD:99783	23/75 (31%)
		FNR_like	<1136..>1178	CDD:297884
		NAD_binding_6	1158..1325	CDD:285298
FRO3	NP_001185067.1	PLN02292	27..717	CDD:215165	88/358 (25%)
		Ferric_reduct	203..317	CDD:280043	40/166 (24%)
		NOX_Duox_like_FAD_NADP	353..536	CDD:99783	36/148 (24%)
		NAD_binding_6	455..700	CDD:285298	6/36 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11972
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910