DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nox and AT1G19230

DIOPT Version :9

Sequence 1:	NP_001097336.1	Gene:	Nox / 5740310	FlyBaseID:	FBgn0085428	Length:	1340	Species:	Drosophila melanogaster
Sequence 2:	NP_001319042.1	Gene:	AT1G19230 / 838506	AraportID:	AT1G19230	Length:	952	Species:	Arabidopsis thaliana

Alignment Length:	1113	Identity:	220/1113 - (19%)
Similarity:	377/1113 - (33%)	Gaps:	421/1113 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 TGFDKSSLARLEQLFRTTVGN----------EQEIRREEFQKIVTSKNPF-----FTERVFQIFD 372
            |...:.:|..|:.:.:||.||          :|..::.|.:....|||..     |.|.|..:..
plant   166 TSSAQRALKGLQFINKTTRGNSCVCDWDCDCDQMWKKVEKRFESLSKNGLLARDDFGECVGMVDS 230

  Fly   373 KDNSGSI----------SLQEFI-DAIHQF----SGQSADDKIRFLFKVYDIDGDGLIQHKELHD 422
            ||.:.|:          .|::.. |.:|.|    |.||.|.:::..|.:.|.:.||.|..:|:.:
plant   231 KDFAVSVFDALARRRRQKLEKITKDELHDFWLQISDQSFDARLQIFFDMADSNEDGKITREEIKE 295

  Fly   423 VIRHCIKENGMEFSEDQIEDLTSAMFEDADPHNSGEITYEALKNQLHKHGGLLENLSITIDRWL- 486
            ::......|.:...::|.|:..|.:.|:.||.|.|.|       :|.:    ||.|.:..|.::
plant   296 LLMLSASANKLAKLKEQAEEYASLIMEELDPENFGYI-------ELWQ----LETLLLQRDAYMN 349

  Fly   487 --VPIAEDRQAGGAAKSGFWNSLPHQFSLAYMKNNQVFVT-------YLFFYITVNLCLFISRAI 542
              .|::  ..:||.:........|........|..|..:.       .|..::.:...||:.:.:
plant   350 YSRPLS--TTSGGVSTPRRNLIRPRHVVQKCRKKLQCLILDNWQRSWVLLVWVMLMAILFVWKFL 412

  Fly   543 QYRASNGFVII------ARACGQCLNFNCAWVLVLMLRHSLTYLRGRGLSSYLPLDHHVYLHKLT 601
            :||....|.::      |:...:.|..|.|.||:.:.|::||:||.....:.:|.|.::..||:.
plant   413 EYREKAAFKVMGYCLTTAKGAAETLKLNMALVLLPVCRNTLTWLRSTRARACVPFDDNINFHKII 477

  Fly   602 GITISVLSLIHTIMHL-FNFSIIVINDPNINAGHYTIGEWLLT------DRPGLFGLIPGCANPT 659
            ...|::..|:|...|| .:|..|:.:.|.         :::|.      .:|....|:.|....|
plant   478 ACAIAIGILVHAGTHLACDFPRIINSSPE---------QFVLIASAFNGTKPTFKDLMTGAEGIT 533

  Fly   660 GVALLAILVVMFVCSQPFVRRK-----------GSFEVFYWTHLLYVPFWILCLFHG-------- 705
            |::::.:..:.|..:....||.           ..|..|::||.|.|..:|:.:.||
plant   534 GISMVILTTIAFTLASTHFRRNRVRLPAPLDRLTGFNAFWYTHHLLVVVYIMLIVHGTFLFFADK 598

  Fly   706 ---PNFWKWFLLPGLVYIVERALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRPHHFNFRPGDY 767
               ...|.:..:|.::|:.||:||.  .|.:|....|....:||.:|:.|::.:|..|.::.|.|
plant   599 WYQKTTWMYISVPLVLYVAERSLRA--CRSKHYSVKILKVSMLPGEVLSLIMSKPPGFKYKSGQY 661

  Fly   768 VFVNIPAIANYEWHPFTISSAPEQEDYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQH 832
            :|:..|.|:.:|||||:|:||| .:|.:.:||||:|:||..|
plant   662 IFLQCPTISRFEWHPFSITSAP-GDDQLSVHIRTLGDWTEEL----------------------- 702

  Fly   833 MHAIPTPSFMLLNEARNPAIAGERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPAT 897

plant   703 ----------------------------------------------------------------- 702

  Fly   898 GVNRIRSIKKTLQRTFSRKEAVDPKKGIPNGAFIADGEREDSNLKQRPLEKSISLPDISVKSKKR 962
              .|:.::.|.|...
plant   703 --RRVLTVGKDLSTC-------------------------------------------------- 715

  Fly   963 SRLKALRALGRSESESAFDEKRVRRARNNSVGLAYLSPQNKSLAQSFRYMRTKPTIIAFKTPSME 1027
                   .:|||:..                  ||.:
plant   716 -------VIGRSKFS------------------AYCN---------------------------- 727

  Fly  1028 EREHQVAAGEANGASPASRAEQGQLSSRMDSADKLQLARLSLSAEGASKPLEDQTQTGSPSRKSI 1092
                                        :|                                  :
plant   728 ----------------------------ID----------------------------------M 730

  Fly  1093 LRRPTFLRSLSASINNRTGGGGGGSTGSSTTNSGGKVTLDAGVMEIFIDGPYGAPSSHIFGAQHA 1157
            :.||                                        ::.:|||||||:.........
plant   731 INRP----------------------------------------KLLVDGPYGAPAQDYRSYDVL 755

  Fly  1158 VLIGTGIGVTPFASILQSIMH--RYWKARHSCPRCQFEWAS-------EIPKSVMNLR----KVD 1209
            :|||.|||.|||.|||:.:::  |..:..:...|..|.|.|       ..|.|....:    |..
plant   756 LLIGLGIGATPFISILKDLLNNSRDEQTDNEFSRSDFSWNSCTSSYTTATPTSTHGGKKKAVKAH 820

  Fly  1210 FFWINRDQRSFEWFVNLLSQLEIEQAELGGAMERFLDMHMYITSALQRTDMKAVGLQLALDLLHE 1274
            |:|:.|:..|.|||..::.  ||...:..|.:|    :|.|:||.....|.::..:::...|.|.
plant   821 FYWVTREPGSVEWFRGVME--EISDMDCRGQIE----LHNYLTSVYDEGDARSTLIKMVQALNHA 879

  Fly  1275 KGKRDLITGLKTRTNAGRPNWDKVFKQL-QAQQKGKVTVFYCGPPQLAKTLRYKCDQYG------ 1332
            |...|:::|.:.||:..||||.:||..: :......|.|||||...:||.|:.:.....
plant   880 KHGVDILSGTRVRTHFARPNWKEVFSSIARKHPNSTVGVFYCGIQTVAKELKKQAQDMSQKTTTR 944

  Fly  1333 FAFRKECF 1340
            |.|.||.|
plant   945 FEFHKEHF 952

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nox	NP_001097336.1	FRQ1	314..466	CDD:227455	42/172 (24%)
		EFh	365..425	CDD:238008	19/74 (26%)
		EFh	399..462	CDD:238008	16/62 (26%)
		Ferric_reduct	560..700	CDD:280043	37/157 (24%)
		NOX_Duox_like_FAD_NADP	744..>819	CDD:99783	29/74 (39%)
		FNR_like	<1136..>1178	CDD:297884	19/41 (46%)
		NAD_binding_6	1158..1325	CDD:285298	57/180 (32%)
AT1G19230	NP_001319042.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	106	1.000	Domainoid score	I2182
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I807
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D936110at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11972
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970