Protein Alignment Nox and RHD2

DIOPT Version :9

• Sequence 1: NP_001097336.1
• Gene: Nox / 5740310
• FlyBaseID: FBgn0085428
• Length: 1340
• Species: Drosophila melanogaster
• Sequence 2: NP_199919.1
• Gene: RHD2 / 835179
• AraportID: AT5G51060
• Length: 905
• Species: Arabidopsis thaliana
• Alignment Length: 1156
• Identity: 229/1156 - (19%)
• Similarity: 399/1156 - (34%)
• Gaps: 429/1156 - (37%)

  Fly   270 ENKRVSFKNFRDIWHTRGILDKLYRLIELDG----------SNLVSTNQV-------MEFISHLT 317
            |.|....|....:.|      :|.||..:.|          :.|..|...       ::|||...
plant    94 EKKTTVVKRLASVSH------ELKRLTSVSGGIGGRKPPRPAKLDRTKSAASQALKGLKFISKTD 152

  Fly   318 NSRPRTGFDKSSLARLEQLFRTTVGNEQEIRREEFQKIV--TSKNPFFTERVFQIFD-----KDN 375
            .....:..:|    |..|:..||.|   .:.|.:|.:.:  |||     :...::||     ::.
plant   153 GGAGWSAVEK----RFNQITATTGG---LLLRTKFGECIGMTSK-----DFALELFDALARRRNI 205

  Fly   376 SGSI----SLQEFIDAIHQFSGQSADDKIRFLFKVYDIDGDGLIQHKELHDVIRHCIKENGMEFS 436
            :|.:    .|:||.:   |.:.||.|.:::..|.:.|.|.||.:...|:.::|......|.:...
plant   206 TGEVIDGDQLKEFWE---QINDQSFDSRLKTFFDMVDKDADGRLTEDEVREIISLSASANNLSTI 267

  Fly   437 EDQIEDLTSAMFEDADPHNSGEITYEALKNQLHKHG--------GLLENLSITIDRWLVPIAEDR 493
            :.:.::..:.:.|:.||.|.|.|..|:|:..|.:..        |..:|||..:.:.|.|.
plant   268 QKRADEYAALIMEELDPDNIGYIMLESLETLLLQAATQSVITSTGERKNLSHMMSQRLKPT---- 328

  Fly   494 QAGGAAKSGFWNSLP----HQFSLAYMKNN--QVFVTYLFFYITVNLCLFISRAIQYRASNGF-- 550
                      :|..|    ::....::.:|  :.:|..|:|.:..  .||..:.||||.|..:
plant   329 ----------FNRNPLKRWYRGLRFFLLDNWQRCWVIVLWFIVMA--ILFTYKYIQYRRSPVYPV 381

  Fly   551 ----VIIARACGQCLNFNCAWVLVLMLRHSLTYLRGR-GLSSYLPLDHHVYLHKLTGITISVLSL 610
                |.:|:...:.:..|.|.:|:.:.|:::|:||.: .|...:|.|.::..||:..:.|.|...
plant   382 MGDCVCMAKGAAETVKLNMALILLPVCRNTITWLRNKTRLGRVVPFDDNLNFHKVIAVGIIVGVT 446

  Fly   611 IHTIMHL-FNFSIIVINDPNINAGHYTIGEWLLTDRP-GLFGLIPGCANPTGVALLAILVVMFVC 673
            :|...|| .:|..::...|.   .:..:.::...::| ..:..:......||:.::.::.:.|..
plant   447 MHAGAHLACDFPRLLHATPE---AYRPLRQFFGDEQPKSYWHFVNSVEGITGLVMVLLMAIAFTL 508

  Fly   674 SQPFVRR------------KGSFEVFYWTHLLYVPFWILCLFHG-----------PNFWKWFLLP 715
            :.|:.||            ..||..|::||.|:|..:||.:.||           ...|.:.::|
plant   509 ATPWFRRGKLNYLPGPLKKLASFNAFWYTHHLFVIVYILLVAHGYYLYLTRDWHNKTTWMYLVVP 573

  Fly   716 GLVYIVERALRFIWMRGEHGKTYISSGLLLPSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEW 780
            .::|..||.:|.  .|.......|....:.|..|:.:.:.||.:|.::.|.|:|||..|::.:||
plant   574 VVLYACERLIRA--FRSSIKAVTIRKVAVYPGNVLAIHLSRPQNFKYKSGQYMFVNCAAVSPFEW 636

  Fly   781 HPFTISSAPEQEDYMWLHIRTVGEWTNRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTPSFMLLN 845
            |||:|:||| |:||:.:|||.:|:||..|             .|...|:
plant   637 HPFSITSAP-QDDYLSVHIRVLGDWTRAL-------------KGVFSEV---------------- 671

  Fly   846 EARNPAIAGERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPATGVNRIRSIKKTLQ 910
                                                          ..||..||:.:
plant   672 ----------------------------------------------CKPPPAGVSGL-------- 682

  Fly   911 RTFSRKEAVDPKKGIPNGAFIADGEREDSNLKQRPLEKSISLPDISVKSKKRSRLKALRALGRSE 975
                                                                     ||
plant   683 ---------------------------------------------------------LR------ 684

  Fly   976 SESAFDEKRVRRARNNSVGLAYLSPQNKSLAQSFRYMRTKPTIIAFKTPSMEEREHQVAAGEANG 1040
                                                                             
plant   685 ----------------------------------------------------------------- 684

  Fly  1041 ASPASRAEQGQLSSRMDSADKLQLARLSLSAEGASKPLEDQTQTGSPSRKSILRRPTFLRSLSAS 1105
                              ||.|         .||:.|
plant   685 ------------------ADML---------HGANNP---------------------------- 694

  Fly  1106 INNRTGGGGGGSTGSSTTNSGGKVTLDAGVMEIFIDGPYGAPSSHIFGAQHAVLIGTGIGVTPFA 1170
                                        ...::.||||||||:......:..:|:|.|||.||..
plant   695 ----------------------------DFPKVLIDGPYGAPAQDYKKYEVVLLVGLGIGATPMI 731

  Fly  1171 SILQSIMHRYWKARHSCPRCQFEWASEIP----KSVMNLRKVDFFWINRDQRSFEWFVNLLSQLE 1231
            ||::.|::.. ||:......:.|..:..|    |.....|:..|:|:.|:|.||:||.|:::::.
plant   732 SIVKDIVNNI-KAKEQAQLNRMENGTSEPQRSKKESFRTRRAYFYWVTREQGSFDWFKNIMNEVA 795

  Fly  1232 IEQAELGGAMERFLDMHMYITSALQRTDMKAVGLQLALDLLHEKGKRDLITGLKTRTNAGRPNWD 1296
            ...|      .|.::||.|.||..:..|.::..:.:...|.|.|...|:::|.:..::..:|||.
plant   796 ERDA------NRVIEMHNYCTSVYEEGDARSALIHMLQSLNHAKNGVDIVSGTRVMSHFAKPNWR 854

  Fly  1297 KVFKQLQAQQKG-KVTVFYCGPPQLAKTLRYKCDQY------GFAFRKECF 1340
            .|:|::...... ||.|||||.|.|.|.||:....:      .|:|.||.|
plant   855 NVYKRIAMDHPNTKVGVFYCGAPALTKELRHLALDFTHKTSTRFSFHKENF 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nox	NP_001097336.1	FRQ1	314..466	CDD:227455	38/162 (23%)
		EFh	365..425	CDD:238008	16/68 (24%)
		EFh	399..462	CDD:238008	14/62 (23%)
		Ferric_reduct	560..700	CDD:280043	33/154 (21%)
		NOX_Duox_like_FAD_NADP	744..>819	CDD:99783	30/74 (41%)
		FNR_like	<1136..>1178	CDD:297884	18/41 (44%)
		NAD_binding_6	1158..1325	CDD:285298	53/171 (31%)
RHD2	NP_199919.1	NADPH_Ox	131..229	CDD:400631	25/112 (22%)
		EF-hand_7	228..290	CDD:404394	14/61 (23%)
		Ferric_reduct	398..548	CDD:396386	34/152 (22%)
		NOX_Duox_like_FAD_NADP	597..905	CDD:99783	111/609 (18%)
		NAD_binding_6	715..888	CDD:369657	55/179 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	106	1.000	Domainoid score	I2182
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I807
OMA	1	1.010	-	-		QHG58487
OrthoDB	1	1.010	-	-		D936110at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.880