DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nox and FRO6

DIOPT Version :9

Sequence 1:	NP_001097336.1	Gene:	Nox / 5740310	FlyBaseID:	FBgn0085428	Length:	1340	Species:	Drosophila melanogaster
Sequence 2:	NP_199784.2	Gene:	FRO6 / 835036	AraportID:	AT5G49730	Length:	738	Species:	Arabidopsis thaliana

Alignment Length:	729	Identity:	146/729 - (20%)
Similarity:	251/729 - (34%)	Gaps:	207/729 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 WLVPIAEDRQAGGAAKSGFWNSLPHQFSLAYMKNNQVFVTYLFFYITVNLCLFISRAIQYRASNG 549
            |..|:..|...|..:.:.|         |..|..:..|:..::.|...||.|.  ........|.
plant   113 WTFPVLVDGPFGVVSAAEF---------LGIMVFSVFFLWSIYAYTLRNLDLL--ERFHVLPKNR 166

  Fly   550 FVIIARACG---QCLNFNCAWVLVLMLRHSLTYLRGRGLSSYLPLDH----HVYLHKLTGITISV 607
            .:::....|   ..:...|...|.|.:......||    ...:|.:|    ||:|..:|....|:
plant   167 SILLLEVTGLRLGMIGLLCMVFLFLPISRGSILLR----LIDIPFEHATRYHVWLGHITMAFFSL 227

  Fly   608 LSLIHTIMHLFNFSII-VINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPTGVALLAILVVMF 671
            ..|.:.:..:....:: :|...|      .||..:|   ||:..|:.|             ::|:
plant   228 HGLCYVVGWIIQGQLLELIFSWN------AIGIAIL---PGVISLVAG-------------LLMW 270

  Fly   672 VCSQPFVRRKGSFEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGL-VYIVERALRFIWMRGEHG 735
            |.|...| ||..||:|::||.||:.|.:....|..::....:..|: ::|::|.|||...|
plant   271 VTSLHTV-RKNYFELFFYTHQLYIVFIVFLALHVGDYMFSIVAGGIFLFILDRFLRFCQSR---- 330

  Fly   736 KTY-ISSGLLLPSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEWHPFTISSAP-EQEDYMWLH 798
            :|. :.|...||...:.||:.:|.:..:....::|:.:..::..:||||::||:| :...::.:.
plant   331 RTVDVISAKSLPCGTLELVLSKPPNMRYNALSFIFLQVRELSWLQWHPFSVSSSPLDGNHHVAVL 395

  Fly   799 IRTVGEWT----NRLYRYFEREQQKLQQSGSSQEIPQHMHAIPTP-----SFMLLNEARNPAIAG 854
            |:.:|.||    ::|...:|.|.|  .|..|.|..|:....:..|     .:.|..| ....:||
plant   396 IKVLGGWTAKLRDQLSNLYEAENQ--DQLISPQSYPKITTCVEGPYGHESPYHLAYE-NLVLVAG 457

  Fly   855 ERSATPQTDFLAKNLGVQAVPPVRPPRQNRKPAPGAPIDPPATGVNRIRSIKKTLQRTFSRKEAV 919
            ....||   |.|                                         .|.....||.
plant   458 GIGITP---FFA-----------------------------------------ILSDILHRKR-- 476

  Fly   920 DPKKGIPNGAFIADGEREDSNLKQRPLEKSISLPDISVKSKKRSRLKALRALGRSESESAFDEKR 984
            |.|..:|:...:....:....|.   |..:|.:|.|.....|:..|:....:.| :||...::..
plant   477 DGKACLPSKVLVVWAIKNSDELS---LLSAIDIPSICPFFSKKLNLEIHIYITR-QSEPRLEDGM 537

  Fly   985 VRRARNNSVGLAYLSPQNKSLAQS---------------------FRYMRTKPTIIAFKTPSM-- 1026
            |.:..:.||.|    |:....:.|                     |..|.|...|...|..::
plant   538 VHKVVHPSVKL----PRTNGCSMSVLVGTGDNIWSGLYLIISTIGFISMITLLDIFYIKRYNITT 598

  Fly  1027 ---------------------------EEREHQVAAGEANGASPASRAEQGQLSSRMDSADKLQL 1064
                                       ...||:....||||......  .|:.:....:|:...|
plant   599 WWYKGLLFVGCMVASVLIFGGLVVVFWHRWEHKTGEVEANGNDKVDL--NGEETHNPSAAELKGL 661

  Fly  1065 ARLSLSAEGASKPLEDQTQTGSPSRKSILRRPTFLRSLSASINNRTGGGGGGSTGSSTTNSGGKV 1129
            |            :|:..|..:..|..  .||.| |.:..|:|.:.|
plant   662 A------------IEEDVQNYTTIRYG--TRPAF-REIFESLNGKWG------------------ 693

  Fly  1130 TLDAGVMEIFIDGP 1143
            ::|.||:   :.||
plant   694 SVDVGVI---VCGP 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nox	NP_001097336.1	FRQ1	314..466	CDD:227455
		EFh	365..425	CDD:238008
		EFh	399..462	CDD:238008
		Ferric_reduct	560..700	CDD:280043	36/144 (25%)
		NOX_Duox_like_FAD_NADP	744..>819	CDD:99783	20/79 (25%)
		FNR_like	<1136..>1178	CDD:297884	2/8 (25%)
		NAD_binding_6	1158..1325	CDD:285298
FRO6	NP_199784.2	PLN02292	24..736	CDD:215165	146/729 (20%)
		Ferric_reduct	181..299	CDD:280043	36/144 (25%)
		NOX_Duox_like_FAD_NADP	335..527	CDD:99783	48/243 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11972
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910