DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nox and FRO4

DIOPT Version :9

Sequence 1:	NP_001097336.1	Gene:	Nox / 5740310	FlyBaseID:	FBgn0085428	Length:	1340	Species:	Drosophila melanogaster
Sequence 2:	NP_197786.2	Gene:	FRO4 / 832463	AraportID:	AT5G23980	Length:	699	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	99/423 - (23%)
Similarity:	175/423 - (41%)	Gaps:	80/423 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   555 RACGQCLNF--NCAWV-LVLMLRHSLTYLRGRGLSSYLPLDHHVYLHKLTGITISVLSLIHTIMH 616
            ||.|..:.:  |..|. |...:..:.|.|...||:|...:.:|::|    |...:...|:||::.
plant   150 RAFGLRIGYVGNICWAFLFFPVTRASTILPLVGLTSESSIKYHIWL----GHVSNFCFLVHTVVF 210

  Fly   617 LFNFSIIVINDPNINAGHYTIGEWLLTDRPGLFGLIPGCANPTGVALLAILVVMFVCSQPFVRRK 681
            |..:::       ||....|.. |..|..|.|.|.|          .:.|.:.|:|.|.|..|||
plant   211 LIYWAM-------INKLMETFA-WNPTYVPNLAGTI----------AMVIGIAMWVTSLPSFRRK 257

  Fly   682 GSFEVFYWTHLLYVPFWILCLFHGPNFWKWFLLPGL-VYIVERALRFIWMRGEHGKTYISSGLLL 745
             .||:|::||.||..:.:..:.|..:.|...:||.: ::.::|.|||:   ....::.:.|..:|
plant   258 -KFEIFFYTHHLYGLYIVFYVIHVGDSWFCMILPNIFLFFIDRYLRFL---QSTKRSRLVSARIL 318

  Fly   746 PSKVVHLVIKRPHHFNFRPGDYVFVNIPAIANYEWHPFTISSAPE-QEDYMWLHIRTVGEWTNRL 809
            ||..:.|...:....::.|...:|:::|:|:..:||||||:|:.. ::|.:.:.||..|.||.:|
plant   319 PSDNLELTFSKTPGLHYTPTSILFLHVPSISKIQWHPFTITSSSNLEKDTLSVVIRRQGSWTQKL 383

  Fly   810 YRYFEREQQKLQQSGSSQEIPQHMHAIPTPSFMLLNEARNPAIAGERSATPQTDFLAKNLGVQAV 874
            |.:.......|:.|......|.........|.:|        ::|....||         .:..:
plant   384 YTHLSSSIDSLEVSTEGPYGPNSFDVSRHNSLIL--------VSGGSGITP---------FISVI 431

  Fly   875 PPVRPPRQNRK-PAPGA-------------------PIDPPATGVNRIR-SIKKTLQRTFSRKEA 918
            ..:....||:. ..|..                   |:|..|:.::|:. .|:..:.|...:.|.
plant   432 RELISQSQNKSTKLPDVLLVCSFKHYHDLAFLDLIFPLDMSASDISRLNLRIEAYITREDKKPET 496

  Fly   919 VDPKKGIPNGAFIADGEREDSNLKQRPLEKSIS 951
            .|..:.:....|           |.:||:..||
plant   497 TDDHRLLQTKWF-----------KPQPLDSPIS 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nox	NP_001097336.1	FRQ1	314..466	CDD:227455
		EFh	365..425	CDD:238008
		EFh	399..462	CDD:238008
		Ferric_reduct	560..700	CDD:280043	39/142 (27%)
		NOX_Duox_like_FAD_NADP	744..>819	CDD:99783	23/75 (31%)
		FNR_like	<1136..>1178	CDD:297884
		NAD_binding_6	1158..1325	CDD:285298
FRO4	NP_197786.2	PLN02631	1..699	CDD:178238	99/423 (23%)
		Ferric_reduct	159..275	CDD:280043	39/138 (28%)
		NOX_Duox_like_FAD_NADP	312..489	CDD:99783	40/193 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11972
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910