Protein Alignment CG41520 and angptl2a

DIOPT Version :10

• Sequence 1: NP_001104019.1
• Gene: CG41520 / 5740294
• FlyBaseID: FBgn0087011
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001025401.1
• Gene: angptl2a / 569092
• ZFINID: ZDB-GENE-080721-15
• Length: 525
• Species: Danio rerio
• Alignment Length: 647
• Identity: 168/647 - (25%)
• Similarity: 249/647 - (38%)
• Gaps: 232/647 - (35%)

  Fly   101 LEGKLKR--IDSLDNTVDLLMKNMETLQNRVVNNVLKTDFIISQLKNIEKTISNE--MLQGQSSN 161
            ||.::.:  ::.|:..:....:.:||||               ||..::..:.||  :|:.:|.|
Zfish    90 LENRVNKQELELLNGELHKQRRQIETLQ---------------QLVEVDGGVVNEVKLLRKESRN 139

  Fly   162 LNVAYETTKITQNSSTLLKEQIVNLDRKVSDIDNKLECMKVQLDNNLLHVEDFNAEASEKKPVTI 226
            :|     .::||....||.|.|    ||   .||.||..  ||:|.:|:
Zfish   140 MN-----ARVTQLYMQLLHEII----RK---RDNALEVS--QLENRVLN---------------- 174

  Fly   227 NVNDVTKALSYVAMTQVTSELSELRDSTDNIDKKLQFYINIASENIGKMTSMMHEIHCAVVHHNN 291
                            .|||:.:|.....:::.|.|...::||
Zfish   175 ----------------HTSEMQQLTSRYRDLEHKYQHLASLAS---------------------- 201

  Fly   292 QFKFLNVTTHSKSNNINKLVKEIRPMGVVSEQNDNVWDVGVDTKSTDGHLLSKSTAPLSQTQRQE 356
                      ::|..|.:|.::.|..|.|.         |..|:.....::...  |....|.::
Zfish   202 ----------NQSAVIVQLEEQCRRGGFVG---------GRQTRPYQPPVVPPQ--PAQTPQHRQ 245

  Fly   357 RAIDEIHHDK----KPKSYLNINNFDMVKKQFEKQENFKPPEEISETRIKEALEYESKNYTDTDE 417
            .....:||..    .|.:|...||                               :..|...:|:
Zfish   246 PPPPPVHHSPARPFHPPTYPRQNN-------------------------------QMTNEIQSDQ 279

  Fly   418 NSRTEILLLSLSNIQPTIVNKTITTPFTSTPGDGDVLGPLHSESLDSNRTHYNGPAVNGLKSANR 482
            ||:      ::.:..||..::|                  ||.|.|.    .:||
Zfish   280 NSK------AMPSALPTEQSET------------------HSFSTDK----LSGP---------- 306

  Fly   483 KDRIIFPSIKKKPAFLNTTISNDFWALKDVKGFSCVDILNAGMKQSGVFYLQIRGTTYWFLKVYC 547
                                      .||     |:..|..|...||:|.|:...|.. .::|:|
Zfish   307 --------------------------FKD-----CLQALEEGHSNSGMFLLKPENTNK-LMQVWC 339

  Fly   548 DQETTDGGWTVIQRRDDFKDSRENFNRDWADYKNGFGEPSKDFWLGNENIYMLTNNEEYSLRVEL 612
            ||....|||||||||   .|...||.|:|..||.|||....::|||.||||.|||...|.|.|.|
Zfish   340 DQRHDPGGWTVIQRR---MDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTL 401

  Fly   613 EDFEGNKRYAQYSHFKIHSEADYYKLEIDGYEGNAGDSLNDPWYGSNNSPFSTYNKDNDRSSLNC 677
            ||:.|.|.:|:|:.|::..|||:||:.:..|.||||||:.  |:  |...|:|.::|:|..:.||
Zfish   402 EDWSGRKTFAEYASFRLEPEADFYKMRVGRYHGNAGDSMT--WH--NGKQFTTLDRDHDAYTGNC 462

  Fly   678 ASMLKGGWWWKSCGR-GLNGL------YLHDPQDITARQGIVWFRWRGWDYTLKKSKMMIRP 732
            |...|||||:.:|.. .|||:      |....||     |:.|..:||..|:|||..|||||
Zfish   463 AHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQD-----GVYWAEFRGGSYSLKKVTMMIRP 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG41520	NP_001104019.1	FReD	516..733	CDD:238040	98/224 (44%)
angptl2a	NP_001025401.1	YhaN	93..>216	CDD:443752	40/215 (19%)
		FReD	305..519	CDD:238040	100/267 (37%)