Protein Alignment CG41520 and Angpt2

DIOPT Version :10

• Sequence 1: NP_001104019.1
• Gene: CG41520 / 5740294
• FlyBaseID: FBgn0087011
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_031452.2
• Gene: Angpt2 / 11601
• MGIID: 1202890
• Length: 496
• Species: Mus musculus
• Alignment Length: 613
• Identity: 158/613 - (25%)
• Similarity: 252/613 - (41%)
• Gaps: 153/613 - (24%)

  Fly   139 IISQLKNIEKTI-SNEMLQGQSSNLNVAY-----ETTKITQNSSTLLKEQI---VNLDRKVSDID 194
            :.|...|..|:: |....|.|..|...:|     ||.....:||..:...:   ..||  ..|..
Mouse    15 LASAYSNFRKSVDSTGRRQYQVQNGPCSYTFLLPETDSCRSSSSPYMSNAVQRDAPLD--YDDSV 77

  Fly   195 NKLECMKVQLDNN---LLHVEDFNAEASEKKPVTINVNDVTKALSYVAMTQVTSELSELRDSTDN 256
            .:|:.::..|:||   |:.:|::..:..:|:.|.|..|.|....:  .|.::.:.|
Mouse    78 QRLQVLENILENNTQWLMKLENYIQDNMKKEMVEIQQNVVQNQTA--VMIEIGTSL--------- 131

  Fly   257 IDKKLQFYINIASENIGKMTSMMHEIHCAVVHHNNQFKFLNVTTHSKSNNINKLVKEIRPMGVVS 321
                    :|..:....|:|    ::...|::...:.: |.:..||.|.  |||.|:|
Mouse   132 --------LNQTAAQTRKLT----DVEAQVLNQTTRLE-LQLLQHSIST--NKLEKQI------- 174

  Fly   322 EQNDNVWDVGVDTKSTDGHLLSKSTAPLSQTQRQERAIDEIHHDKKPKSYLNINNFDMVKKQFEK 386
                                       |.||       .||:..:...|:|.....||..|..|:
Mouse   175 ---------------------------LDQT-------SEINKLQNKNSFLEQKVLDMEGKHSEQ 205

  Fly   387 QENFKPPEEISETRIKEALEYESKNYTDTDENSRTEILLLSLSNIQPTIVNKTITTPFTSTPGDG 451
            .::.|                        ::....::|:...|::...:..|.:|...
Mouse   206 LQSMK------------------------EQKDELQVLVSKQSSVIDELEKKLVTATV------- 239

  Fly   452 DVLGPLHSESLDSNRTHYNGPAVNGL----KSANRKDRIIFPSIKKKPAFLNTTISNDFWALKDV 512
                   :.||...:.|.....||.|    .|.|.|..:   :|:|:.   .||..:
Mouse   240 -------NNSLLQKQQHDLMETVNSLLTMMSSPNSKSSV---AIRKEE---QTTFRD-------- 283

  Fly   513 KGFSCVDILNAGMKQSGVFYLQIRGTTYWFLKVYCDQETTDGGWTVIQRRDDFKDSRENFNRDWA 577
                |.:|..:|:..||::.|....:|. .:|.|||.:...|||||||.|:   |...:|.|.|.
Mouse   284 ----CAEIFKSGLTTSGIYTLTFPNSTE-EIKAYCDMDVGGGGWTVIQHRE---DGSVDFQRTWK 340

  Fly   578 DYKNGFGEPSKDFWLGNENIYMLTNNEEYSLRVELEDFEGNKRYAQYSHFKIHSEADYYKLEIDG 642
            :||.|||.|..::|||||.:..||....|.|:::|:|:|||:.::.|.||.:..|...|::.:.|
Mouse   341 EYKEGFGSPLGEYWLGNEFVSQLTGQHRYVLKIQLKDWEGNEAHSLYDHFYLAGEESNYRIHLTG 405

  Fly   643 YEGNAG--DSLNDPWYGSNNSPFSTYNKDNDRSSLNCASMLKGGWWWKSCG-RGLNGLYLHDPQD 704
            ..|.||  .|::.|     .|.|||.:.|||:....|:.||.||||:.:|| ..|||.|....|:
Mouse   406 LTGTAGKISSISQP-----GSDFSTKDSDNDKCICKCSQMLSGGWWFDACGPSNLNGQYYPQKQN 465

  Fly   705 ITARQGIVWFRWRGWDYTLKKSKMMIRP 732
            .....||.|:.|:|..|:||.:.|||||
Mouse   466 TNKFNGIKWYYWKGSGYSLKATTMMIRP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG41520	NP_001104019.1	FReD	516..733	CDD:238040	88/220 (40%)
Angpt2	NP_031452.2	Mplasa_alph_rch	<78..>232	CDD:275316	40/244 (16%)
		FBG	280..494	CDD:214548	89/235 (38%)