Protein Alignment Vml and egr1

DIOPT Version :9

• Sequence 1: NP_001096866.1
• Gene: Vml / 5740271
• FlyBaseID: FBgn0085362
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_571323.1
• Gene: egr1 / 30498
• ZFINID: ZDB-GENE-980526-320
• Length: 511
• Species: Danio rerio
• Alignment Length: 500
• Identity: 113/500 - (22%)
• Similarity: 175/500 - (35%)
• Gaps: 129/500 - (25%)

  Fly     6 LLFLAAFGCLLANAFSLPATRNEEFDDGFPESEFDY-------EERHTREIPAQAYA----PPIV 59
            ::.|.:.|....||   .|.....|..|.|..:||:       |....:.:..|.|:    |||.
Zfish    35 MIMLNSAGTPFLNA---TAPEGAVFGSGEPGEQFDHLAGDTLSEISMEKPLSDQTYSTQRLPPIS 96

  Fly    60 YNSQSSYSPAKDQGYSAPAAPVYSPAAPSYSAPAAPSYSAPAAPSYSAPAAPSYSAPAAPSYSAP 124
            |..:.:..||.:...|..|.|::|..:........|: |.|:  |.|....||       |.|..
Zfish    97 YTGRFTLEPATNCSNSLWAEPLFSLVSGLVGINPPPA-SIPS--STSQATHPS-------SSSTS 151

  Fly   125 AAPSYSAPASSSYSAPAAPSYSAPAAPSYSAPAAPSYSAPASSSYSAPAAPSYSAPAAPS--YSA 187
            :.||.|:.::||.|...:...|.| .|.||  |||:||: ||......:.|::|.....|  ||:
Zfish   152 SIPSSSSSSTSSASLSCSVHQSEP-NPIYS--AAPTYSS-ASPDIFPESGPNFSTTVGTSLQYSS 212

  Fly   188 PAAPSYSAPAAPSYSAPAAPSYSAPAAPSYSAPSAPSYSAQKTSSYSAPAAPSYHAPAA------ 246
            ...|| :....||:|.|..|.|......|..:...|.....:|.:...||....|...|
Zfish   213 STYPS-AKTCNPSFSVPMIPDYLFTQQQSEISLVPPDQKPIQTQAGQQPALTPLHTIKAFATQTG 276

  Fly   247 --------------PASSYSAPAGPSYSAPAAPSYSAP--------------------------- 270
                          |:.....|..||.:.|....|:.|
Zfish   277 SQDLKSVYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPF 341

  Fly   271 -------SYSAPASSYSALKAPSYSAP-----------------------------AAPSYSAPA 299
                   ::|......:.::..:...|                             .|...:..|
Zfish   342 QCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAA 406

  Fly   300 APSYSSSASPSYSSPASSSYSAPAAPTYSAPKAQSYSAPAAPSYSAPAAPSYSAPASSSYSAPAA 364
            ..|..|:.|.|.|||. |||.:|..         ||.:|.: |:.:|....||:|..:||.:|:.
Zfish   407 VQSSVSNISISASSPV-SSYPSPIT---------SYPSPVS-SFPSPVNSCYSSPVHTSYPSPSI 460

  Fly   365 PSYSAPAAPSYSAPAAPSY-SAPASSSYSAPAA---PSYSAPAAP 405
            .:....|..::....|.|: ::.||:.||:|..   |...:..:|
Zfish   461 ATTYPSATSTFQTQVATSFPTSVASNIYSSPVTTPLPDMQSALSP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vml	NP_001096866.1	None
egr1	NP_571323.1	DUF3446	99..185	CDD:288757	29/98 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..169		14/45 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..312		5/20 (25%)
		zf-C2H2	311..335	CDD:278523	2/23 (9%)
		C2H2 Zn finger	313..335	CDD:275368	1/21 (5%)
		zf-H2C2_2	327..352	CDD:290200	0/24 (0%)
		C2H2 Zn finger	343..363	CDD:275368	1/19 (5%)
		zf-H2C2_2	355..380	CDD:290200	1/24 (4%)
		C2H2 Zn finger	371..391	CDD:275368	0/19 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..406		1/21 (5%)
		DUF3432	403..498	CDD:288743	31/105 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000