Protein Alignment RhoGAP1A and chin-1

DIOPT Version :9

• Sequence 1: NP_001284725.1
• Gene: RhoGAP1A / 5740235
• FlyBaseID: FBgn0025836
• Length: 1404
• Species: Drosophila melanogaster
• Sequence 2: NP_497323.3
• Gene: chin-1 / 175268
• WormBaseID: WBGene00015267
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 442
• Identity: 98/442 - (22%)
• Similarity: 157/442 - (35%)
• Gaps: 140/442 - (31%)

  Fly  1014 SSDFERTQWIDSILSLKQKCNLPGA-------------------NTINSLEVTAFIVAMQKGMKT 1059
            ||...:..|..::..|::|...|.|                   ..|:..|....:      ::.
 Worm     9 SSGASKGYWKQNLYLLQEKAPKPNAVLCRKPLQQRPRHFGAEFHGLIDRNEAEKML------LEA 67

  Fly  1060 EMGSYLMRNTNDE-----------------------------------SLLVGD----LYMGVHG 1085
            ..||||:|.:|..                                   .|||.|    :::.:|.
 Worm    68 GEGSYLVRESNRSRDACTLCMIFDAKVMNYKLYYDGQFYVGEKRFDTMDLLVADGLISMFVDLHA 132

  Fly  1086 LEGLEQANDLYICVEVDSYGHYFR-KATTKKICRSQTPLWNESFMLELEGSQNVRILLYEAKERP 1149
            .:.:::..|..| .|...|..|.. .|||..|.|                             ||
 Worm   133 ADYIKRMADEAI-YEDSPYSRYTNAAATTSDIVR-----------------------------RP 167

  Fly  1150 LLKAKHILKLSLSWLTETTQPKSIKLTETLELGCSF--RFIPGELFRG----------------- 1195
            :.:|.:....:..      .|..          |.:  .|:.|.:.:|
 Worm   168 VTRAHNFTSYTFK------APHY----------CDYCRNFLWGLVHQGMRCEDCGFAAHKKCSEK 216

  Fly  1196 --------STKPGALFGAKMSQVLKREKRDIPFIIGACIREVERRGMLEVGCYRVSGSASDLAKL 1252
                    |.....:||..::.:......|:|.|:..||.|||.||:...|.||||||...:.||
 Worm   217 TLHDCVPDSKYVKRMFGVDITTLCMAHGADLPPIVPLCIGEVESRGLDVEGIYRVSGSYDHMEKL 281

  Fly  1253 KKAFESDAYEAEQLLREVDIHSVTGILKTFLRELPEALFTDQLYPRFFDTFSAFSNNNESTRINE 1317
            |:.|:|:.|  ..|....|||:|.|:||.:.|.||:.|....::.:....:...:..:...|..:
 Worm   282 KQQFDSNQY--VDLATVCDIHTVCGLLKLYFRLLPQQLIPFSVHKQLLVAYQETNQRSTHERERQ 344

  Fly  1318 LLKVFEELPQANKASITSILDHLIRVHEKETDNKMSLHNLAMVFGPTLLRPG 1369
            :.||..||..||..::.::|.||.:|.:....|||::.|||.:|.|||...|
 Worm   345 IRKVMMELSDANIITLGAVLAHLKKVADHSAKNKMTVENLATIFSPTLFCSG 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP1A	NP_001284725.1	RhoGEF	675..857	CDD:214619
		PH_BCR_arthropod	851..1037	CDD:270174	5/22 (23%)
		C2	1079..1187	CDD:301316	16/110 (15%)
		RhoGAP	1203..1398	CDD:295372	59/167 (35%)
chin-1	NP_497323.3	SH2_a2chimerin_b2chimerin	43..130	CDD:198215	12/92 (13%)
		C1_1	172..224	CDD:278556	5/67 (7%)
		RhoGAP	248..413	CDD:238090	56/151 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I4545
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1094
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940