DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and Ttc12

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_006243066.1	Gene:	Ttc12 / 300696	RGDID:	1303264	Length:	723	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	49/202 - (24%)
Similarity:	98/202 - (48%)	Gaps:	11/202 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PKPELFIYQHPAADESFLKEQPTKVEDVIEYLDVLENANKTDSSKKRQKSTITMDDIKCIVTR-- 85
            |.|.|......|.|:.  ::....:|:|.|..::::..| :|....:||:.:..:....::.|
  Rat    10 PPPALRFVSAMADDQE--RDLQRFLENVDEITNLIQEMN-SDDPFIQQKAVLDTEKKLLLMEREQ 71

  Fly    86 -----RSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEPDDRVLAREQREDVAETFRRMGNYEYR 145
                 |:.::.|.....:|.......|...|:..::.:..:|...|.:...:|:..:..||..:.
  Rat    72 EEDGCRTTLNKTMISPPQAPENANEMNPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFV 136

  Fly   146 KLNFSLAKDYYSKGIQYIKDSPVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAA 210
            |.::..|..:||:|:..:||..|||.|||..:|||.:::..::|||:.| |.||:..:|:.:...
  Rat   137 KGDYETAIFFYSEGLGKLKDMKVLYTNRAQAYIKLGDYQKALVDCDWAL-KCDENCTKAYFHMGK 200

  Fly   211 AYKRLND 217
            |:..|.:
  Rat   201 AHLALKN 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	22/61 (36%)
		TPR repeat	133..161	CDD:276809	8/27 (30%)
		TPR repeat	166..197	CDD:276809	13/30 (43%)
Ttc12	XP_006243066.1	TPR_11	124..189	CDD:290150	24/65 (37%)
		TPR repeat	124..152	CDD:276809	8/27 (30%)
		TPR repeat	157..187	CDD:276809	13/30 (43%)
		TPR_11	160..223	CDD:290150	18/49 (37%)
		TPR_1	161..191	CDD:278916	14/30 (47%)
		TPR repeat	192..217	CDD:276809	3/16 (19%)
		TPR_1	193..224	CDD:278916	3/15 (20%)
		ARM	631..723	CDD:237987
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005389
OrthoInspector	1	1.000	-	-		otm44459
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810