DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and cns1

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_594238.1	Gene:	cns1 / 2542172	PomBaseID:	SPAC17A2.04c	Length:	358	Species:	Schizosaccharomyces pombe

Alignment Length:	167	Identity:	40/167 - (23%)
Similarity:	72/167 - (43%)	Gaps:	32/167 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 FMRQIDSEPDD----------RVLARE-QREDVAETFRRMGNYEYRKLNFSLAKDYYSKGI-QYI 163
            ||:.::...|:          :.||.| :..:||:.||..||..:....:..|:::|:|.: |..
pombe    31 FMQSLEDVGDESENNVQLDALKALAYEGEPHEVAQNFREHGNECFASKRYKDAEEFYTKALAQKC 95

  Fly   164 KDSPV---LYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAA----AYKRLND---- 217
            .|..:   .|.|||.|.:....::..:.||..||.: |..:.:|: ||:|    |.||.::
pombe    96 GDKDIEIACYSNRAACNLLFENYRQVLNDCAQVLQR-DSTHAKAY-YRSAKALVALKRYDEAKEC 158

  Fly   218 -------EPNFEYSVDRARRFNRSDADFIDEFLDKMR 247
                   .||....:..::...:...||.....:|.|
pombe   159 IRLCSLVHPNDPAILALSKELQKKSDDFEKRESEKKR 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	18/65 (28%)
		TPR repeat	133..161	CDD:276809	8/28 (29%)
		TPR repeat	166..197	CDD:276809	9/33 (27%)
cns1	NP_594238.1	TPR_11	64..132	CDD:290150	19/68 (28%)
		TPR repeat	64..92	CDD:276809	8/27 (30%)
		TPR repeat	97..131	CDD:276809	10/33 (30%)
		TPR_19	116..175	CDD:291240	14/60 (23%)
		TPR repeat	136..160	CDD:276809	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910