DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34274 and Stip1

DIOPT Version :9

Sequence 1:NP_001097807.1 Gene:CG34274 / 5740212 FlyBaseID:FBgn0085303 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_058017.1 Gene:Stip1 / 20867 MGIID:109130 Length:543 Species:Mus musculus


Alignment Length:241 Identity:52/241 - (21%)
Similarity:100/241 - (41%) Gaps:52/241 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 PKPELFIYQHPAADESFLKEQ--------------------------PTKVEDVIEYLDVLENAN 61
            ||||......|...:..|||:                          ||.:..:.....|  :..
Mouse   209 PKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAV--HFE 271

  Fly    62 KTDSSKKRQ--KSTITM-----DDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEP 119
            |.|.:|.|:  :..|.:     :|.:.|....:.:..:.|:..|.|.|:...|:.....:   .|
Mouse   272 KGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHR---TP 333

  Fly   120 D--------DRVLAREQR-----EDVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDSPVLYV 171
            |        :::|..::|     .|:|...:..||..::|.::..|..:|::.|:.......||.
Mouse   334 DVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYS 398

  Fly   172 NRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLND 217
            |||.|:.||.||:|.:.||:..: :::..:::.:..:|||.:.:.|
Mouse   399 NRAACYTKLLEFQLALKDCEECI-QLEPTFIKGYTRKAAALEAMKD 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34274NP_001097807.1 TPR_11 133..195 CDD:290150 20/61 (33%)
TPR repeat 133..161 CDD:276809 6/27 (22%)
TPR repeat 166..197 CDD:276809 13/30 (43%)
Stip1NP_058017.1 TPR 1 4..37
TPR_11 6..69 CDD:290150
TPR 7..37 CDD:197478
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR 2 39..71
TPR_11 40..100 CDD:290150
TPR repeat 72..100 CDD:276809
TPR 3 73..105
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..233 8/23 (35%)
Bipartite nuclear localization signal. /evidence=ECO:0000255 222..239 3/16 (19%)
TPR_11 224..287 CDD:290150 10/64 (16%)
TPR 4 225..258 4/32 (13%)
TPR repeat 229..253 CDD:276809 0/23 (0%)
TPR_1 231..258 CDD:278916 1/26 (4%)
TPR_12 255..328 CDD:290160 15/74 (20%)
TPR repeat 258..288 CDD:276809 6/31 (19%)
TPR 5 260..292 6/33 (18%)
TPR 6 300..333 5/35 (14%)
TPR 300..328 CDD:197478 5/27 (19%)
TPR repeat 300..328 CDD:276809 5/27 (19%)
TPR_11 360..425 CDD:290150 20/65 (31%)
TPR 7 360..393 7/32 (22%)
TPR_1 364..393 CDD:278916 6/28 (21%)
TPR repeat 364..388 CDD:276809 5/23 (22%)
TPR_11 393..458 CDD:290150 17/52 (33%)
TPR repeat 393..423 CDD:276809 13/30 (43%)
TPR_1 394..427 CDD:278916 13/33 (39%)
TPR 8 395..427 13/32 (41%)
TPR 9 428..461 4/16 (25%)
TPR repeat 428..456 CDD:276809 4/16 (25%)
STI1 492..531 CDD:128966
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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