DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34274 and Stip1

DIOPT Version :9

Sequence 1:NP_001097807.1 Gene:CG34274 / 5740212 FlyBaseID:FBgn0085303 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_620266.1 Gene:Stip1 / 192277 RGDID:621599 Length:543 Species:Rattus norvegicus


Alignment Length:239 Identity:53/239 - (22%)
Similarity:108/239 - (45%) Gaps:31/239 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PLTTNTVDKKNE--HEKPFGLEIPKPELFIYQHPAADESFLKE-QPTKVEDVIEYLDVLENANKT 63
            |:..:..:.|.:  .||..|.:..|.:.|.......|::  || .||.:..:.....|  :..|.
  Rat   213 PMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDKA--KELDPTNMTYITNQAAV--HFEKG 273

  Fly    64 DSSKKRQ--KSTITM-----DDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEPD- 120
            |.:|.|:  :..|.:     :|.:.|....:.:..:.|:..:.|.|:...|:.....:   .|| 
  Rat   274 DYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHR---TPDV 335

  Fly   121 -------DRVLAREQR-----EDVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDSPVLYVNR 173
                   :::|..::|     .|:|...:..||..::|.::..|..:|::.|:.......||.||
  Rat   336 LKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNR 400

  Fly   174 ALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLND 217
            |.|:.||.||:|.:.||:..: :::..:::.:..:|||.:.:.|
  Rat   401 AACYTKLLEFQLALKDCEECI-QLEPTFIKGYTRKAAALEAMKD 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34274NP_001097807.1 TPR_11 133..195 CDD:290150 20/61 (33%)
TPR repeat 133..161 CDD:276809 6/27 (22%)
TPR repeat 166..197 CDD:276809 13/30 (43%)
Stip1NP_620266.1 TPR 1 4..37
3a0801s09 <7..532 CDD:273380 53/239 (22%)
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR 2 39..71
TPR repeat 72..100 CDD:276809
TPR 3 73..105
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..233 4/19 (21%)
Bipartite nuclear localization signal. /evidence=ECO:0000255 222..239 5/16 (31%)
TPR 4 225..258 9/34 (26%)
TPR repeat 229..253 CDD:276809 5/25 (20%)
TPR repeat 258..288 CDD:276809 6/31 (19%)
TPR 5 260..292 6/33 (18%)
TPR 6 300..333 4/35 (11%)
TPR repeat 300..328 CDD:276809 4/27 (15%)
TPR 7 360..393 7/32 (22%)
TPR repeat 364..388 CDD:276809 5/23 (22%)
TPR repeat 393..423 CDD:276809 13/30 (43%)
TPR 8 395..427 13/32 (41%)
TPR 9 428..461 4/16 (25%)
TPR repeat 428..456 CDD:276809 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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