DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	238	Identity:	64/238 - (26%)
Similarity:	106/238 - (44%)	Gaps:	59/238 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PWMAFIASPTKN-CSGTLINKQYVITTASCVFD---QSESTVFLG---RFDN-IPQNRNRYVKHS 97
            ||...:.....: |.|::|...:::|.|.||:|   ....||.:|   ..|: :|       .|.
Mouse   251 PWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVP-------SHL 308

  Fly    98 VQSVYTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICI-------------WLGEITNLNHLES 149
            |:.:..|..|..:...:||||:.|.:|:||..:|||||:             |           :
Mouse   309 VEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCW-----------T 362

  Fly   150 NRWGLSE-----KMIFQRINTVKILKIKKC--RDSFGITLKKSQICAGFQNGNI--CT-ETGSSL 204
            :.||.:|     ..:.... .|.::..|.|  ||.:|..:..|.:|||:..|.:  |. ::|..|
Mouse   363 SGWGATEDGGDASPVLNHA-AVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPL 426

  Fly   205 VKQIHYSGKLWNTLIGIQSYG-----VSERCIYNKIAHYIDWI 242
            |.|   ..:||. |:|..|:|     |::..:|.:|..::|||
Mouse   427 VCQ---ERRLWK-LVGATSFGIGCAEVNKPGVYTRITSFLDWI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	62/236 (26%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	62/236 (26%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133
		Tryp_SPc	238..465	CDD:214473	62/236 (26%)
		Tryp_SPc	239..468	CDD:238113	64/238 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910