DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and AgaP_AGAP012020

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_320509.4	Gene:	AgaP_AGAP012020 / 1280648	VectorBaseID:	AGAP012020	Length:	753	Species:	Anopheles gambiae

Alignment Length:	233	Identity:	62/233 - (26%)
Similarity:	102/233 - (43%)	Gaps:	47/233 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 TPWMAFIASPTKNCSGTLINKQYVITTASCVFDQSESTVFLGRFD--NIPQNR-NRYVKH-SVQS 100
            |.|:         |.|:||.:.:::|.|.|..|::.:...:.|..  ||..|. |.|.:. .:..
Mosquito    45 TKWL---------CGGSLIRENFILTAAHCTADENNTPPDVARMGDLNIYSNADNEYAQELKIVD 100

  Fly   101 VYTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICIWLGEITNLNHLESNRW---GLSEKMIFQR 162
            |..|..|...:..:||||:.|:..|:....:.|.|:||.:.....:|.:..|   |.||
Mosquito   101 VIRHPNYKFTSSYYDIALMKLERNVSVTRYVIPTCLWLEDEIRFPNLMAAGWGRTGFSE------ 159

  Fly   163 INTVKIL-KIK-------KCRDSF---------GITLKKSQICAGFQNGNICT-ETGSSLVKQIH 209
             ||.:|| |::       ||...:         |  |...|:|||.:..:.|. ::|..|...:.
Mosquito   160 -NTSEILMKVQLSPVREDKCLKHYRKGDYKYRNG--LLDHQLCAGDEEMDTCPGDSGGPLHVMLL 221

  Fly   210 YSGKLWNTLIGIQSY----GVSERCIYNKIAHYIDWIV 243
            ...||...|:|:.|:    ||....:|.|::.:.|||:
Mosquito   222 KDKKLVPFLVGVTSFGKICGVPAPGVYIKVSKFGDWII 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	60/230 (26%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	60/230 (26%)
AgaP_AGAP012020	XP_320509.4	Tryp_SPc	17..258	CDD:214473	60/230 (26%)
		Tryp_SPc	18..261	CDD:238113	62/233 (27%)
		Tryp_SPc	317..536	CDD:304450
		Trypsin	323..533	CDD:278516
		Tryp_SPc	641..>732	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910