DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34437 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	75/288 - (26%)
Similarity:	122/288 - (42%)	Gaps:	72/288 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DFEC--VNHKPHQDVFKET--------------PWMAFIASPTKN---CSGTLINKQYVITTASC 69
            :|||  |.::.:   ||.|              |::|.|....:.   |:|.||..|:|:|.:.|
Mosquito  1062 NFECGKVRNRKY---FKATKRIVGGSTSNPGDWPFIAAILGGPEEVFYCAGVLIADQWVLTASHC 1123

  Fly    70 VFDQSES---------TVFLGRFDNIPQNRNRYV---KHSVQSVYTHKLYNKQ-TFEHDIALLLL 121
            :.:...|         |:.||    |.:.|:...   |..|::|..|.:||.. ..::||||..|
Mosquito  1124 IGNSPTSHTMRNVNDWTIQLG----ITRRRSHTYYGQKVKVKTVIPHPMYNLHIPHDNDIALFQL 1184

  Fly   122 DDPVTFKMSIQPICI---WLGEI-TNLN----------HLESNRWGLSEKMIFQRINTVKILKIK 172
            ...|.|...:.|:|:   .:.|: |.:|          ...|...|.|.:.....:| |.|:..:
Mosquito  1185 ATRVAFHEHLLPVCLPPPHIRELPTGINCTVVGWGKREERNSTPNGASYEPTLNEVN-VPIVSRE 1248

  Fly   173 KCRD---SFGITLKKSQICAGFQNG--NICT-ETGSSLVKQIHYSGKLWNTLIGIQSYGVSERC- 230
            .|.|   :|.:|  :..||||:|.|  :.|. ::|..|:.........| .:.||.|:||  ||
Mosquito  1249 LCIDWLETFNVT--EGMICAGYQEGGRDACQGDSGGPLLCPYPNEKDRW-FVGGIVSWGV--RCA 1308

  Fly   231 ------IYNKIAHYIDWIVGVVLNVDVI 252
                  :|..:..:|.||:..:.|..|:
Mosquito  1309 HPKLPGVYANVPKFIPWILAQINNHSVL 1336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	65/259 (25%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	65/259 (25%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	64/256 (25%)
		Tryp_SPc	1080..1326	CDD:238113	64/255 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910