DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and AgaP_AGAP008808

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_557970.3	Gene:	AgaP_AGAP008808 / 1275666	VectorBaseID:	AGAP008808	Length:	574	Species:	Anopheles gambiae

Alignment Length:	298	Identity:	67/298 - (22%)
Similarity:	116/298 - (38%)	Gaps:	75/298 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LCFLFTLVLAHQGSAYFLDFECVNHKPH--------QDVF----------KETPWMAFI-----A 47
            :|.....||...|..||:...|...:.:        |.||          ...||.|.|     .
Mosquito     3 MCCSLKRVLLLFGFLYFMSRACGQEENYLTCGRRKVQSVFLIHNGVDAKAGHWPWHAAIFHGNGR 67

  Fly    48 SPTKNCSGTLINKQYVITTASCVF------DQSESTVFLGRFDNIPQNRNRYVK-HSVQSVYTHK 105
            .....|.|:::::..::|.:.||:      ..:..:|.:|:..  .:..:.|.: |.||.:..|.
Mosquito    68 QEEYQCGGSILDQNTILTASHCVYTHKSVISAARVSVHVGQIH--LKETSEYTQIHGVQDIILHP 130

  Fly   106 LYNKQTFEHDIALLLLDDPVTFKMSIQPICIWLGEITNLNHLESNR------------WGLSEKM 158
            .:|..:|.:|||||.|...:|....:||:|:|.        ::||:            :||:|..
Mosquito   131 EFNSNSFNNDIALLKLSTNITMTKYVQPVCLWT--------MDSNQEMIVGKNGTIVGFGLNEHD 187

  Fly   159 IFQ------RINTVKILK-IKKCRDSFGITLKKSQICAGFQNG-NICT-ETGSSLVKQIHYSGKL 214
            :..      .:..|..|. ||..|.:||..|.....|...:.| ..|. ::|..:..::   |..
Mosquito   188 VVSDQLKQALVGVVDALTCIKSDRAAFGPVLTSEMFCGKGRTGVGACNGDSGGGMFFEV---GGK 249

  Fly   215 WNTLIGIQSY----GVSERC------IYNKIAHYIDWI 242
            | .:.|:.|:    |.:..|      .|..:|.|::||
Mosquito   250 W-FVRGLVSFTPLRGNTGLCDPLKYTAYTDVAKYLEWI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	55/245 (22%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	55/245 (22%)
AgaP_AGAP008808	XP_557970.3	Tryp_SPc	44..288	CDD:238113	57/257 (22%)
		Tryp_SPc	46..286	CDD:214473	55/253 (22%)
		Tryp_SPc	324..566	CDD:304450
		Tryp_SPc	330..566	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910