DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and AgaP_AGAP008558

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_314667.4	Gene:	AgaP_AGAP008558 / 1275424	VectorBaseID:	AGAP008558	Length:	574	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	63/239 - (26%)
Similarity:	107/239 - (44%)	Gaps:	49/239 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PWMAFI-----ASPTKNCSGTLINKQYVITTASCV-FDQSESTVFLGRFDNIPQNRNR-YV---- 94
            ||.|.|     .|....|.|.:||:..::|.|.|| .:|...||     |.:.....| |:
Mosquito    49 PWHAAIFHRIERSFMYQCGGAIINQNTILTAAHCVQLNQGVITV-----DRLSVQVGRTYLYAAE 108

  Fly    95 ----KHSVQSVYTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICIWLGEITNLNHLESN----- 150
                :|..:.:..|:.|:.....:||||:.|...:.|...:||:|:|....|::..|...
Mosquito   109 SHTQEHQAERIIVHEEYSAAQVRNDIALIKLATDIRFTEYVQPVCLWDRARTDIGQLIGRVGTVI 173

  Fly   151 RWGLSEKMIFQ-----RINTVKILKIKKC----RDSFGITLKKSQICAGFQNG-NIC-TETGSSL 204
            .:|::|  |.:     |:..:.|:..:.|    |:.||..|.::..||||:|| .:| .::|..:
Mosquito   174 GFGITE--IGEVADRLRVAYMPIVDTQTCLESNRNLFGRVLTRNVFCAGFRNGTTVCGGDSGGGM 236

  Fly   205 VKQIHYSGKLWNTLIGIQSYGVSERCI------YNKIAHYIDWI 242
            ..:|.   ..| .:.||.|:. .:.|.      ::.:|.|:|||
Mosquito   237 YFEIE---NRW-YIRGIVSFS-GQNCQSADFAGFSDVATYLDWI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	61/237 (26%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	61/237 (26%)
AgaP_AGAP008558	XP_314667.4	Tryp_SPc	37..277	CDD:238113	63/239 (26%)
		Tryp_SPc	37..275	CDD:214473	61/237 (26%)
		Tryp_SPc	322..568	CDD:214473
		Tryp_SPc	322..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910