DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and AgaP_AGAP003686

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_313469.4	Gene:	AgaP_AGAP003686 / 1274361	VectorBaseID:	AGAP003686	Length:	368	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	65/288 - (22%)
Similarity:	106/288 - (36%)	Gaps:	102/288 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VNHKPHQDVFKET----------------------PWMAFI-------ASPTKNCSGTLINKQYV 63
            ||| |:..:|..|                      ||||.|       .:.:..|:||:||.:||
Mosquito   106 VNH-PNIRLFDRTNCGLPGTVNKIAFGQQARLFQYPWMAMIVYVSNTTGTESSECAGTIINVRYV 169

  Fly    64 ITTASCVFDQSEST--VFLGRFDN------------IPQNRNRYVKHSVQSVYTHKLYNKQTFE- 113
            :|.|.|:..|.|..  |.:|.:|.            .|..|     :.|:....|..:.:....
Mosquito   170 LTAAHCIDGQMERMRYVRIGEYDTRTDPDCEEDTCAAPIQR-----YGVEDAIFHPNFTRIVRSG 229

  Fly   114 HDIALLLLDDPVTFKM-SIQPICI--------------WLGEITNLNHLESNRWGLSEKMIFQRI 163
            |||.||.|:..:.|.. .:.|:|:              |:           ..|||:|::....:
Mosquito   230 HDIGLLRLNRSIDFSSGDVSPVCLPFTTGLMGFDPTLYWI-----------TGWGLTERLEVSPV 283

  Fly   164 NTVKILKIKKCRDSFGITLKKSQICAGFQNGNICTE--TGSSLVKQI-HYSGKLWNTLIGIQSYG 225
            .....:....|      :|....|||||.|..:..|  :|..:..|: .|:.:.      :| ||
Mosquito   284 LLQARIPPVSC------SLSSYAICAGFGNATLHCEGDSGGPMKAQVPEYNFRF------VQ-YG 335

  Fly   226 V---SERC-------IYNKIAHYIDWIV 243
            |   ..||       |.::::.::.||:
Mosquito   336 VISAGPRCGTQGVPGISSRVSFFMQWIL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	58/274 (21%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	58/274 (21%)
AgaP_AGAP003686	XP_313469.4	CLIP	16..75	CDD:288855
		Tryp_SPc	131..362	CDD:214473	57/259 (22%)
		Tryp_SPc	131..362	CDD:238113	57/259 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910