DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and CLIPB5

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_313032.4	Gene:	CLIPB5 / 1273975	VectorBaseID:	AGAP004148	Length:	379	Species:	Anopheles gambiae

Alignment Length:	264	Identity:	67/264 - (25%)
Similarity:	111/264 - (42%)	Gaps:	68/264 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 ETPWMAFI--ASPTK----NCSGTLINKQYVITTASCVFDQS-EST-----VFLGRFD------- 84
            |.||:|.:  |.|..    :|.|.|||.:||:|.:.||..:. .||     |.||.:|
Mosquito   126 EFPWIALLKYAKPNNVFGFHCGGVLINDRYVLTASHCVNGKDIPSTWNLAEVRLGEWDTSTAQDC 190

  Fly    85 --------------NIPQNRNRYVKHSVQSVYTHKLYNKQTFE--HDIALLLLDDPVTFKMSIQP 133
                          ::|          ::....|..|...:.|  :|||||.|...|.:...|:|
Mosquito   191 EGLGDDVDCSPPPIDVP----------IEGKIPHPEYVPTSAEQYNDIALLRLQQSVPYSDFIKP 245

  Fly   134 ICIWL-GEITNLNH----LESNRWGLSEKMIFQRIN---TVKILKIKKCRDSF---GITLKKSQI 187
            ||:.: .|:...::    ::...||.:....|..:.   .|..:.:..|...:   .:.|::||:
Mosquito   246 ICLPMQAELKARDYVGFRMQVAGWGRTATARFSNVKQKVAVDGVSLDACNQVYQREQVLLRQSQL 310

  Fly   188 CAGFQNG-NICTETGSSLVKQIHYSGKL--WNTLIGIQSYGVSERC-------IYNKIAHYIDWI 242
            |||.:.| :.|.......:..:|.:|.|  | .|||:.|:|.:. |       :|.|:..|:|||
Mosquito   311 CAGGEAGKDSCQGDSGGPLTGVHTAGGLQYW-YLIGLVSFGPTP-CGQAGWPGVYTKVDQYVDWI 373

  Fly   243 VGVV 246
            ...:
Mosquito   374 TATI 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	65/258 (25%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	65/258 (25%)
CLIPB5	XP_313032.4	CLIP	33..87	CDD:288855
		Tryp_SPc	115..373	CDD:214473	65/258 (25%)
		Tryp_SPc	116..373	CDD:238113	65/258 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910