DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and AgaP_AGAP007280

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_308537.4	Gene:	AgaP_AGAP007280 / 1269883	VectorBaseID:	AGAP007280	Length:	2275	Species:	Anopheles gambiae

Alignment Length:	237	Identity:	59/237 - (24%)
Similarity:	93/237 - (39%)	Gaps:	73/237 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NCSGTLINKQYVITTASCV--FDQSESTV---FLGRFDNIPQNRNRYVKHSVQSVYTHKLYNKQT 111
            :|.|::.|:.::|:.|.|.  |||....|   .|.:....||.:...|.|.:    .|..|:...
Mosquito   966 HCGGSIYNEHWIISAAHCCDNFDQHYFEVRSGMLRKRSFAPQVQITRVTHMI----VHHAYSSSL 1026

  Fly   112 FEHDIALLLLDDPVTFKMSIQPICI-----------WLGEITNLNHLESNRWGLSEKMIFQRIN- 164
            ..:||||:.::.|..:...::|||:           |:             ||.....:...|.
Mosquito  1027 MANDIALMRVEHPFHYNRWVRPICMPERHRTTDDRDWI-------------WGPKAGTVCTAIGW 1078

  Fly   165 ----------------TVKIL---KIKKCRDSFGITLKKSQICAGFQNG--NICT-ETGSSLVKQ 207
                            :|.||   |.|..|||.       ||||..::|  :.|. ::|...|.|
Mosquito  1079 GALRERGGAPDHLMQVSVPILGYCKHKSDRDSL-------QICAAEEDGGHDACQGDSGGPFVCQ 1136

  Fly   208 IHYSGKLWNTLIGIQSYGVSERC-------IYNKIAHYIDWI 242
            ...:...| .|.|:.|:|  |.|       :|.::|.:||||
Mosquito  1137 SKSNPFEW-YLAGVVSHG--EGCARAHEPGVYTRVALFIDWI 1175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	57/235 (24%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	57/235 (24%)
AgaP_AGAP007280	XP_308537.4	LDLa	698..733	CDD:238060
		Tryp_SPc	941..1175	CDD:214473	57/235 (24%)
		Tryp_SPc	942..1178	CDD:238113	59/237 (25%)
		LDLa	1196..1226	CDD:238060
		LDLa	1510..1541	CDD:238060
		LDLa	1574..1609	CDD:238060
		DUF1986	1774..1887	CDD:286432
		LDLa	1999..2025	CDD:238060
		LDLa	2038..2071	CDD:238060
		LDLa	2107..2142	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910