DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and tmprss3

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	64/240 - (26%)
Similarity:	98/240 - (40%)	Gaps:	62/240 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PWMA-FIASPTKNCSGTLINKQYVITTASCVFD---QSESTVFLGRFDNIPQNRNRYVKHSVQSV 101
            ||.| .:......|.|:||..|:::|.|.||:|   .....|.:|:.....::....|  .||.:
Frog   256 PWQASLVFQGVHLCGGSLITPQWIVTAAHCVYDLLYPEWWRVQVGQVSQASESAQTAV--PVQKI 318

  Fly   102 YTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICI-------------WLGEITNLNHLESNRWG 153
            ..|..|...|..:||||:.|..|.||..||||||:             |:           :.||
Frog   319 IYHSKYRSSTMANDIALIRLASPFTFNGSIQPICLPNYREDFPEGKICWI-----------SGWG 372

  Fly   154 LSEK--------------MIFQRINTVKILKIKKCRDSFGITLKKSQICAGFQNGNICTETGSSL 204
            .:|:              :|..|:...|.:        :|..:|.|.:||||..|.:.|..|.|.
Frog   373 ATEEGGDTSQTMDYAGVPLISNRVCNTKYI--------YGGVIKPSMVCAGFLEGGVDTCQGDSG 429

  Fly   205 VKQIHYSGKLWNTLIGIQSYGVSERC-------IYNKIAHYIDWI 242
            .........:|. |:|..|:|:.  |       :|.:|:.::|||
Frog   430 GPLACEDSNVWK-LMGTTSWGIG--CALRYKPGVYTRISSFLDWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	62/238 (26%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	62/238 (26%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055
		Tryp_SPc	244..472	CDD:238113	64/240 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910