DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34437 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001097955.1	Gene:	CG34437 / 5740179	FlyBaseID:	FBgn0085466	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	236	Identity:	57/236 - (24%)
Similarity:	102/236 - (43%)	Gaps:	55/236 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PWMAFIASPTKN-CSGTLINKQYVITTASCVFDQSES---TVFLGRFDNIPQNRNRYVK-HSVQS 100
            ||...:....:: |.|::|..::::|.|.||:..:..   .|:.| ...:|.|.   || .:|:.
Zfish   310 PWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIAYPMYWMVYAG-LTELPLNA---VKAFAVEK 370

  Fly   101 VYTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICI-------------WLGEITNLNHLESNRW 152
            :..|..|..:..:|||||:.|..|:||...::|||:             |:           :.|
Zfish   371 IIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDGKMCWI-----------SGW 424

  Fly   153 GLSE----KMIFQRINTVKILKIKKCR--DSFGITLKKSQICAGFQNG--NICT-ETGSSLVKQI 208
            |.:|    ..:.|...:|.::..|.|.  :.:...|....||||:.:|  :.|. ::|..|..:
Zfish   425 GATEDGGDASVSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACE- 488

  Fly   209 HYSGKLWNTLIGIQSYGVSERC-------IYNKIAHYIDWI 242
              ...:|. |:|..|:|  :.|       :|.:|...:.||
Zfish   489 --DSSIWK-LVGATSWG--QGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:214473	55/234 (24%)
CG34437	NP_001097955.1	Tryp_SPc	39..242	CDD:304450	55/234 (24%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845
		Tryp_SPc	298..525	CDD:238113	57/236 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910