Protein Alignment Drgx and PHO2

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_010177.1
• Gene: PHO2 / 851452
• SGDID: S000002264
• Length: 559
• Species: Saccharomyces cerevisiae
• Alignment Length: 523
• Identity: 100/523 - (19%)
• Similarity: 168/523 - (32%)
• Gaps: 152/523 - (29%)

  Fly    52 QRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDE 116
            ||..||....:.|:.|:..|.....|.:..|:.::..|.:.|..|::||||||||.||    |..
Yeast    77 QRPKRTRAKGEALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRK----KQH 137

  Fly   117 QRKRENGESSSSLDKLHDSRESSPD-------ITGEI--DDDM---DDLPPRQR----------- 158
            ...::...||.|.|..:|....|.|       .|..|  |:|:   |.:|....
Yeast   138 GSNKDTIPSSQSRDIANDYDRGSTDNNLVTTTSTSSIFHDEDLTFFDRIPLNSNNNYYFFDICSI 202

  Fly   159 ---SHSPLANGQMEQQHSHSHSHSHSRSP----------GGGMHLDSSDNER------------- 197
               |.:.:.:|.:::::..|.....:.||          ...|.|.|..|..
Yeast   203 TVGSWNRMKSGALQRRNFQSIKELRNLSPIKINNIMSNATDLMVLISKKNSEINYFFSAMANNTK 267

  Fly   198 -------PLSS-NQLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGGQGPSSPSNSRNT 254
                   |||| ...:.|..:....:.|.:....:.|..:.:.::..  .......:|..:.||.
Yeast   268 ILFRIFFPLSSVTNCSLTLETDDDIINSNNTSDKNNSNTNNDDDNDD--NSNEDNDNSSEDKRNA 330

  Fly   255 DSPIEVGGPMSLT-TGSRMAA--SSNNSASSTPTPTTPHAPQMPHSSAAAAAAFGSHIFGNFGGG 316
            ....   |.:.|| |.|...|  ..||:....|....       ..|.....:.|..:...|.||
Yeast   331 KDNF---GELKLTVTRSPTFAVYFLNNAPDEDPNLNN-------QWSICDDFSEGRQVNDAFVGG 385

  Fly   317 SNASDSNCGFRPVLSEQSAVAAAAAAAAAQRSANHPPLFLPPHLAAQFTHQPLFPGLKGVSPFQS 381
            ||...:..|.      |.::....:.....:|:|.                 :.|.:....|..:
Yeast   386 SNIPHTLKGL------QKSLRFMNSLILDYKSSNE-----------------ILPTINTAIPTAA 427

  Fly   382 LCSCCSLKPPPPPGSSVVAPLSIPVSSSSAASSPESPKSSGQGSVHDPRSNSVAEL--------- 437
            :           |..: :||..:..:||:..|:|.:.........||..|:|:...
Yeast   428 V-----------PQQN-IAPPFLNTNSSATDSNPNTNLEDSLFFDHDLLSSSITNTNNGQGSNNG 480

  Fly   438 RRKAQEHSAALLQSLHAAAAAGLAFPGLHLPPLSFAHHPALGQHVVNHNNNNTMRMK--HEAQDM 500
            |:.:::.:..||.:                              .||.|||:....:  |.||:.
Yeast   481 RQASKDDTLNLLDT------------------------------TVNSNNNHNANNEENHLAQEH 515

  Fly   501 TMN 503
            ..|
Yeast   516 LSN 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	19/55 (35%)
		OAR	428..446	CDD:461067	4/26 (15%)
PHO2	NP_010177.1	COG5576	53..183	CDD:227863	34/109 (31%)