Protein Alignment Drgx and MIXL1

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001269331.1
• Gene: MIXL1 / 83881
• HGNCID: 13363
• Length: 240
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 73/312 - (23%)
• Similarity: 98/312 - (31%)
• Gaps: 145/312 - (46%)

  Fly    14 GPHPPRLPTLDYPF---AATHPYTSYSYHPAIHDETFVRRKQRRNRTTFTLQQLEELETAFAQTH 75
            ||.||...:|..|.   .|..|..|                |||.||:|:.:||:.||..|.:|.
Human    61 GPAPPPPASLGSPAPPKGAAAPSAS----------------QRRKRTSFSAEQLQLLELVFRRTR 109

  Fly    76 YPDVFTREDLAMKINLTEARV--------QVWFQNRRAKWRKAERLKDEQRKRENGESSSSLDKL 132
            |||:..||.||....|.|:|:        ||||||||||.|           |::|
Human   110 YPDIHLRERLAALTLLPESRIQLLFSPLFQVWFQNRRAKSR-----------RQSG--------- 154

  Fly   133 HDSRESSPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHSHSHSRSPGGGMHLDSSDNER 197
                                     :|..|||..::...|....:.:....|...:.:|
Human   155 -------------------------KSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD------ 188

  Fly   198 PLSSNQLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGGQGPSSPSNSRNTDSPIEVGG 262
               .|.|                  |.|:|          ||||....||...:..|.|
Human   189 ---VNCL------------------PEPNG----------VGGGISDSSSQGQNFETCS------ 216

  Fly   263 PMSLTTGSRMAASSNNSASSTPTPTTPHAPQMPHSSAAAAAAFGSHIFGNFG 314
            |:|...||::                              .::..|||..||
Human   217 PLSEDIGSKL------------------------------DSWEEHIFSAFG 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	31/63 (49%)
		OAR	428..446	CDD:461067
MIXL1	NP_001269331.1	Homeodomain	87..151	CDD:459649	32/74 (43%)