DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Drgx and uncx

DIOPT Version :10

Sequence 1:NP_001097075.2 Gene:Drgx / 5740176 FlyBaseID:FBgn0085369 Length:587 Species:Drosophila melanogaster
Sequence 2:XP_005164261.1 Gene:uncx / 798510 ZFINID:ZDB-GENE-080509-1 Length:483 Species:Danio rerio


Alignment Length:431 Identity:112/431 - (25%)
Similarity:164/431 - (38%) Gaps:112/431 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 KQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRK------ 109
            |:||.||.||..||||||.||.::||||||.||.||::::|.|:|||||||||||||||      
Zfish    99 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLIESRVQVWFQNRRAKWRKKENTKK 163

  Fly   110 ----------------------------AERLKDEQRKRENG--ESSSSL---DKLHDSRESSPD 141
                                        .|||:.::||:|..  :|.:.|   |..|.....|..
Zfish   164 GPGRPAHNSHPTTCSGEPMDPEEIARRELERLEKKKRKQERRLLKSQNKLLPGDLFHTPGSDSDS 228

  Fly   142 ITGEIDDDMDDLPPRQRSHSPLANGQ----MEQQHSHSHSHSHSRSPGGGMHLDSSDNERPLSSN 202
            ...:|.|.      .|..|..:...|    .:|......:..::.....|..|||||:.:  .||
Zfish   229 GLSQITDS------EQSLHCDMGRNQTQPSCDQTPQKLQNQRNADQDASGSELDSSDSGQ--QSN 285

  Fly   203 QLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGGQGPSSPSNSRNTDSPIEVGGPM--- 264
            ..:.:..||.|.|...|..|.....  |.|...|:                 |.|:....|:   
Zfish   286 LCSNSRSSALQKLNPFSVESLLSDS--RPRRKPPM-----------------DFPVPTPRPLIGK 331

  Fly   265 ------SLTTGSRMAASSNNSASSTPTPTTPHAPQMPHSSAAAAAAFGSHIFGNFG----GGSNA 319
                  .:|.............|:.|.|.|.:..:.|.:....|        ||.|    ..:|:
Zfish   332 GHFLLYPITQPLGFIVPQTALKSTAPGPDTENGQKGPATDITFA--------GNPGHRNAKENNS 388

  Fly   320 SDSNCGFRPV---LSEQSAVAAAAAAAAAQRSANHPPLFLPPHLAAQFTHQ-PLFPGLKGVSPFQ 380
            .::|.|.|.:   :|:...::.:..:::.|.:.|       .|.|.....: |....|:.|.|  
Zfish   389 VNNNSGARAIKGQVSQSGNISCSTQSSSPQTTIN-------GHSAGSCNERCPQDIELELVDP-- 444

  Fly   381 SLCSCCSLKPPPPPGSSVVAPLSIPVSSSSAASSPESPKSS 421
                    |.|.........|...|.:|.||.:|.::.|.|
Zfish   445 --------KSPQSEKKEQSLPDYPPQNSESATTSKDTDKDS 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DrgxNP_001097075.2 Homeodomain 53..109 CDD:459649 39/55 (71%)
OAR 428..446 CDD:461067
uncxXP_005164261.1 COG5576 <88..208 CDD:227863 48/108 (44%)
Homeodomain 101..157 CDD:459649 39/55 (71%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.