DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Drgx and repo

DIOPT Version :9

Sequence 1:	NP_001097075.2	Gene:	Drgx / 5740176	FlyBaseID:	FBgn0085369	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	96/363 - (26%)
Similarity:	127/363 - (34%)	Gaps:	107/363 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 KQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKD 115
            |:::.|||||..||||||.||.:..|||||.||:||:|:||:|:|||||||||||||||.|
  Fly   303 KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHE---- 363

  Fly   116 EQRKRENGESSSSLDKLHDSRESSPDIT---GEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHS 177
              ..|:.|...:|         :.|..|   |.:.......|.......|   |.|:...|:...
  Fly   364 --PPRKTGYIKTS---------TPPTATLNPGTLAPPFTSYPQTTTVTPP---GSMDSWTSYQTP 414

  Fly   178 H---------SHSRSPGGGMHLDSSDNERPLSSNQLTATPHSASQ-SLGSISAGSPSPSGMHRER 232
            :         |.:.||.|            ..|.|..|..|.:.. .:.....|||:...|
  Fly   415 YELTPQFSLLSPAASPYG------------TYSGQYGAYVHESQLFPMRHYEYGSPTRMEM---- 463

  Fly   233 EHTPLVGGGGQGPSSPSNSRNTDSPIEVGGPMSLTTGSRMAASSNNSASSTPTPTTPHAPQM--- 294
                       |.::.|.:.|.|..:..||  |..|.....|.....|..|......|..|.
  Fly   464 -----------GATTGSVAGNGDESVANGG--SYQTAELQTAQQQQLADGTLVTVHAHQQQQQQQ 515

  Fly   295 ------------------------------PHSSAAAAAAFGSHIF-----GNFGGGSNASDSN- 323
                                          |.:|.....|.|.|..     |....|..:||.|
  Fly   516 QQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTATGGAASAGGTSSDDND 580

  Fly   324 -CGFRPVLSEQSAVAAAAAAAAAQRSANHPPLFLPPHL 360
             .|.:.|:..:.       .:..|:........|||.|
  Fly   581 SGGMQTVIKSEE-------VSQQQQQQQGQSYVLPPFL 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeobox	56..108	CDD:278475	38/51 (75%)
Drgx	NP_001097075.2	OAR	428..445	CDD:281777
repo	NP_477026.1	Homeobox	313..360	CDD:278475	33/46 (72%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.010