DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drgx and Pph13

DIOPT Version :9

Sequence 1:	NP_001097075.2	Gene:	Drgx / 5740176	FlyBaseID:	FBgn0085369	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	104/345 - (30%)
Similarity:	146/345 - (42%)	Gaps:	96/345 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DETFVRRKQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWR 108
            |:..::|||||.||||...||:|||.||.:|||||||.||:||::|:||||||||||||||||||
  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66

  Fly   109 KAERLKDEQRKRENGESSSSLDKLHDSRESSPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHS 173
            |.|::        .|...       |.:|.:.|:....||.             ...||::
  Fly    67 KQEKI--------GGLGG-------DYKEGALDLDVSYDDS-------------AVLGQLD---- 99

  Fly   174 HSHSHSHSRSPGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSISAGSPSPS-GMHREREHTPL 237
                   |...|||..|..:.   |.|||.|. ....||...|::|....||: .::...:|..|
  Fly   100 -------SALGGGGTLLPDTP---PQSSNSLD-NELKASYGTGAMSPSRLSPNIFLNLNIDHLGL 153

  Fly   238 VGGGG-------------QGPSSPSNSRNTDSPIEVGGPMS-----LTTGSRMAASSNNSASSTP 284
            ..||.             |..:.|  ..::|:.::...|..     :..||    ||::......
  Fly   154 ERGGSGLSMEWSTYPPQTQAQTHP--QMDSDNQLQQHPPQQHASDPIHAGS----SSHHQQQQQQ 212

  Fly   285 TPTTPHAPQMPHSSAAAAAAFGSHIFGNFGGGSNASD------------------SNCGFRPVLS 331
            .....|.||: |.....||:...    :...||:|.|                  ::|    :||
  Fly   213 HQQEQHNPQL-HPGLEFAASLSL----DMTDGSSAYDEMKFLSVDVDQFTIDSFKADC----ILS 268

  Fly   332 -EQSAVAAAAAAAAAQRSAN 350
             |||.:.|....:....|:|
  Fly   269 MEQSQMQAYGGHSQLVGSSN 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeobox	56..108	CDD:278475	39/51 (76%)
Drgx	NP_001097075.2	OAR	428..445	CDD:281777
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	39/51 (76%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D143142at50557
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020