Protein Alignment Drgx and Vsx2

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 158/602 - (26%)
• Similarity: 223/602 - (37%)
• Gaps: 210/602 - (34%)

  Fly     4 YQCPPALHPCGPH-----PPRLPTLDYPFAATHPYTSYSYHPAIHDETF---------------- 47
            :|..|..||..||     ||..|    |....||:  :.:||.:|.:.|
  Fly   144 HQHHPHHHPHHPHGAVGGPPPPP----PMQHHHPH--HPHHPLLHAQGFPQLKSFAAGAGTCLPG 202

  Fly    48 -----------------------VRRKQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKI 89
                                   .::|:|.:||.||..|||:||.||.:.|||||:.||.|::|.
  Fly   203 SLAPKDFGMESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKT 267

  Fly    90 NLTEARVQVWFQNRRAKWRKAERLKDEQRKRENGESSSSLDKLHDS--RES--SPDITGEIDDDM 150
            .|.|.|:|||||||||||||.|::       ..|.:..:...|:.:  |.|  .||...:...|.
  Fly   268 ELPEDRIQVWFQNRRAKWRKTEKV-------WGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDN 325

  Fly   151 DDLPPRQRSHSPLANGQMEQQHSHSHS---HSHSRSPGG-GMHLDSSDNERPLSSNQLTATPHSA 211
            |.:.|....        |||:..|..|   .|..:...| ..|.||:.::...|.:...:..|:.
  Fly   326 DAVAPWLLG--------MEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHAL 382

  Fly   212 SQSLGSISAGSPSPSGMHREREHTPLVGGGGQGPSSPSNSRNTDSPIEVGGPMSLTTGSRMAASS 276
            |.|..|::..||:||..                |:|.|.|....|.....|..|....:...||:
  Fly   383 SSSTESLNVVSPAPSSC----------------PTSASTSAPPTSTSGYAGAASSAATTPTGAST 431

  Fly   277 NNSASS------TPTPTTPHAPQMPHSSAAAAAAF---GSHIFG-------------NFGGGSNA 319
            .||:||      :|:|......|:.......|:.:   |:.:.|             | ..|:.|
  Fly   432 TNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAAN-AAGAGA 495

  Fly   320 SDSNCGFRPVLSEQSAVAAAAAAAAAQRSANHPPLFLPPHLAAQFTHQ---PLFPGLKGVSPFQS 381
            :.|:..|..:::  :|||||||||..|            |...|...|   ...|||.
  Fly   496 AASSKDFHMIMN--TAVAAAAAAAQQQ------------HQQQQQQQQQATATAPGLH------- 539

  Fly   382 LCSCCSLKPPPPPGSSVVAPLSIPVSSSSAASSPESPKSSGQGSVHDP---RSNSVAELRRKAQE 443
                                     :.:.||:..|          |||   |:||:|.||.||||
  Fly   540 -------------------------AHNLAAALME----------HDPDAFRNNSIACLRAKAQE 569

  Fly   444 HSAALLQSLHAAAAAGLAFPGLHLPPLSFAHHPALGQHVV-----------NHNNNNTMRM--KH 495
            |.|.||.:           .||.|....||.    ||..:           .||||:.:.:  .|
  Fly   570 HQARLLNN-----------GGLFLQVRRFAQ----GQAQIQDPSDMLKLSEEHNNNSPIPIPPAH 619

  Fly   496 EA--------QDMTMNG 504
            ..        .::|.||
  Fly   620 STVNTQVNVKMELTANG 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	35/55 (64%)
		OAR	428..446	CDD:461067	13/20 (65%)
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	35/56 (63%)
		OAR	556..572	CDD:461067	11/15 (73%)