DRSC/TRiP Functional Genomics Resources

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Protein Alignment Drgx and GSC2

DIOPT Version :10

Sequence 1:NP_001097075.2 Gene:Drgx / 5740176 FlyBaseID:FBgn0085369 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_005306.1 Gene:GSC2 / 2928 HGNCID:4613 Length:205 Species:Homo sapiens


Alignment Length:130 Identity:53/130 - (40%)
Similarity:67/130 - (51%) Gaps:18/130 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CYQCPPALHPCGP------------HPPRL-PTLDYPFAATHPYTSYSYHP-AIHDETFVRRKQR 53
            |..|.|...||||            .|.|| |.:  |.:...|.......| |:...:  :|:.|
Human    67 CCCCGPRAAPCGPPEAAAGLGARLAWPLRLGPAV--PLSLGAPAGGSGALPGAVGPGS--QRRTR 127

  Fly    54 RNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDEQR 118
            |:||.|:.:||:.||..|.|..||||.|||.||.:|.|.|.||:|||:|||||||..:|.....|
Human   128 RHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKRASASAR 192

  Fly   119  118
            Human   193  192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DrgxNP_001097075.2 Homeodomain 53..109 CDD:459649 34/55 (62%)
OAR 428..446 CDD:461067
GSC2NP_005306.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 33..58
Homeodomain 127..183 CDD:459649 34/55 (62%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..205 2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

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