Protein Alignment Drgx and Shox2

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_038693.1
• Gene: Shox2 / 20429
• MGIID: 1201673
• Length: 331
• Species: Mus musculus
• Alignment Length: 222
• Identity: 70/222 - (31%)
• Similarity: 107/222 - (48%)
• Gaps: 45/222 - (20%)

  Fly    42 IHDETFVRRKQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAK 106
            :.||...:.||||:||.|||:||.|||..|.:|||||.|.||:|:.::.|:||||||||||||||
Mouse   130 MEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAK 194

  Fly   107 WRKAERLKDEQRKRENGESSSSLDKLHD-------SRESSPDITGEIDDDMDDLPPRQRSH---S 161
            .||.|                  ::||.       |:..:..:...::.....:|.:|.||   :
Mouse   195 CRKQE------------------NQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNVT 241

  Fly   162 PLANGQMEQQ--------HSHSHSHSHSRSPGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSI 218
            || :.|::.|        |:|.|.|.|..:....|...:.....||::  |.|...||:..:.:.
Mouse   242 PL-SFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLAT--LAADSASAASVVAAA 303

  Fly   219 SAGSPSPSGMH------REREHTPLVG 239
            :|...:.....      :.::|...:|
Mouse   304 AAAKTTSKNSSIADLRLKAKKHAAALG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	37/55 (67%)
		OAR	428..446	CDD:461067
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..140		2/9 (22%)
		Homeodomain	141..197	CDD:459649	37/55 (67%)
		OAR	311..327	CDD:461067	1/15 (7%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	313..326		0/12 (0%)