DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drgx and ceh-8

DIOPT Version :9

Sequence 1:	NP_001097075.2	Gene:	Drgx / 5740176	FlyBaseID:	FBgn0085369	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_492246.2	Gene:	ceh-8 / 191617	WormBaseID:	WBGene00000433	Length:	276	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	78/267 - (29%)
Similarity:	110/267 - (41%)	Gaps:	71/267 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 RKQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLK 114
            :||||||||||..||..||.||.:||||||:.||.||.|:.|.|.||||||||||||:|:.|: :
Worm    58 KKQRRNRTTFTTFQLHALEAAFDKTHYPDVYARETLAAKVQLPEVRVQVWFQNRRAKFRRQEK-Q 121

  Fly   115 DEQRKRENGESSSSLDKLHDSRESSPDITGEIDDDMDD---LPPRQRSHSPLANGQMEQ------ 170
            |.|     ||...||      :::.|..:...::..|.   |||.....|...||..::
Worm   122 DCQ-----GEEKHSL------KDTMPSWSWMSENKTDTPPMLPPANTLSSTHNNGISDEFFKTSE 175

  Fly   171 ----------QHSHSHSHSHSRSPGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSISAGSPSP 225
                      ::.....::|....|...||:..|:::               :|:...|..:||.
Worm   176 GKEVYGFPFAEYGTPADNTHVSKTGNVFHLNFEDSDK---------------KSMKKESPQTPST 225

  Fly   226 SGMHREREHTPLVGGGGQGPSSPSNSRNTDSPIEVGGPMSLTTGSRMAASSNNSASSTPTPTTPH 290
            |.......|.|.:                        |..:...| .:.:.|......|.|....
Worm   226 SSPFISEYHPPFI------------------------PYYIPNQS-FSNAFNQYPMPFPYPIHFE 265

  Fly   291 APQMPHS 297
            .||:.||
Worm   266 PPQLTHS 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeobox	56..108	CDD:278475	36/51 (71%)
Drgx	NP_001097075.2	OAR	428..445	CDD:281777
ceh-8	NP_492246.2	Homeobox	64..116	CDD:278475	36/51 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920