Protein Alignment Drgx and Pdx1

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 163
• Identity: 47/163 - (28%)
• Similarity: 69/163 - (42%)
• Gaps: 32/163 - (19%)

  Fly     7 PPALHPCGPHP-----PRLPTLDYPF---AATHPYT------SYSYHPAIHDETFVRRKQRRNRT 57
            ||...|.|..|     |....|.:|:   ...|.:.      :|:..|         .:.:|.||
Mouse    97 PPGPFPNGTEPGGLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYTAEP---------EENKRTRT 152

  Fly    58 TFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDEQRKREN 122
            .:|..||.|||..|....|.....|.:||:.:||||..:::||||||.||:     |:|.:||.:
Mouse   153 AYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWK-----KEEDKKRSS 212

  Fly   123 GESSSSLDKLHDSRESSPDITGEIDDDMDDLPP 155
            |..|..    ....|...|......:::..:||
Mouse   213 GTPSGG----GGGEEPEQDCAVTSGEELLAVPP 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	26/55 (47%)
		OAR	428..446	CDD:461067
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		6/18 (33%)
		Antp-type hexapeptide	119..124		1/4 (25%)
		Homeodomain	148..204	CDD:459649	26/60 (43%)
		Nuclear localization signal	198..204		4/10 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		11/49 (22%)