Protein Alignment Drgx and Cdx1

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 249
• Identity: 59/249 - (23%)
• Similarity: 81/249 - (32%)
• Gaps: 108/249 - (43%)

  Fly     8 PALHPCGPHPPRL-PTLDYPFAATHP----YTSYSYHPAIHDETFVRR-----------KQR--- 53
            |...|.||.|..| .:|..|.|.:.|    .|.|.:         :||           |.|
Mouse   100 PVPAPPGPGPGILAQSLGAPGAPSSPGAPRRTPYEW---------MRRSVAAAGGGGSGKTRTKD 155

  Fly    54 RNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDEQR 118
            :.|..:|..|..|||..|..:.|..:..:.:||..:.|||.:|::||||||||.||..:.|.:|:
Mouse   156 KYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQ 220

  Fly   119 KRENGESSSSLDKLHDSRESSPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHSHSHSRS 183
            :                                .|||.|
Mouse   221 Q--------------------------------PLPPTQ-------------------------- 227

  Fly   184 PGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSIS------AGSPSPSGMHRE 231
                         .||   .|..||..:...|||:.      .|:|||..:..|
Mouse   228 -------------LPL---PLDGTPTPSGPPLGSLCPTNAGLLGTPSPVPVKEE 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	23/58 (40%)
		OAR	428..446	CDD:461067
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		15/60 (25%)
		Caudal_act	13..140	CDD:461413	14/48 (29%)
		Homeodomain	156..211	CDD:459649	22/54 (41%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		7/20 (35%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		6/10 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		21/131 (16%)