Protein Alignment Drgx and Phox2a

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_446321.2
• Gene: Phox2a / 116648
• RGDID: 621323
• Length: 281
• Species: Rattus norvegicus
• Alignment Length: 281
• Identity: 100/281 - (35%)
• Similarity: 130/281 - (46%)
• Gaps: 81/281 - (28%)

  Fly     8 PALHPCGPHPPRLPTLDYPFAATH-----PYTS--YSYHP---AIHDETFVRRKQRRNRTTFTLQ 62
            ||....||..|.|.:.:....|..     ||::  |.:.|   .:|:    :|||||.|||||..
  Rat    40 PAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHE----KRKQRRIRTTFTSA 100

  Fly    63 QLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDEQ-------RKR 120
            ||:|||..||:|||||::|||:||:||:||||||||||||||||:||.||....:       .|:
  Rat   101 QLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGATGAKK 165

  Fly   121 ENGESSSSLDKLHDSRES----SPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHSHSHS 181
            .....||..|   ||:||    :||.|.       .|||...:.| ||:.::          |.|
  Rat   166 GEARCSSEDD---DSKESTCSPTPDSTA-------SLPPPPPAPS-LASPRL----------SPS 209

  Fly   182 RSPGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGGQGP- 245
            ..|..   |.|....:||.               |::.||               :.||||.||
  Rat   210 PLPAA---LGSGPGPQPLK---------------GALWAG---------------VAGGGGGGPG 241

  Fly   246 SSPSNSRNTDSPIEVG-GPMS 265
            :..:.......|.|.| ||.|
  Rat   242 AGAAELLKAWQPAEPGPGPFS 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	42/55 (76%)
		OAR	428..446	CDD:461067
Phox2a	NP_446321.2	Homeodomain	91..147	CDD:459649	42/55 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..219		26/97 (27%)