DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drgx and alx4

DIOPT Version :9

Sequence 1:	NP_001097075.2	Gene:	Drgx / 5740176	FlyBaseID:	FBgn0085369	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_004913406.1	Gene:	alx4 / 100493396	XenbaseID:	XB-GENE-853003	Length:	376	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	86/238 - (36%)
Similarity:	109/238 - (45%)	Gaps:	44/238 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 KQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKD 115
            |:||||||||..||||||..|.:||||||:.||.|||:.:|||||||||||||||||||.||...
Frog   180 KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQ 244

  Fly   116 EQRKRENGESSSSLDKLHDSRESSPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHSHSH 180
            .|:.|.:..|:..|          |.:|            |..:::.:.|            .|.
Frog   245 MQQVRTHFSSAYEL----------PLLT------------RAENYAQIQN------------PSW 275

  Fly   181 SRSPGGGMHLDSSDNERPLSSNQLTATPHSASQSLGSIS--AGSPSPSGMHREREHT-PLVGGGG 242
            ..:.|||..:.:.  ..|..:.....:|||...|.|.:|  ...|.| |.|..:.|. .|.|...
Frog   276 IGNNGGGSPVPAC--VVPCDTVSSCMSPHSHPHSAGGVSEFLSVPGP-GAHVGQTHMGGLFGSAA 337

  Fly   243 QGPSSPSNSRNTDSPIEVGGPMSLTTGSRMAASSNNSASSTPT 285
            .||.......||    |.....|.....||.|..:::|.|..|
Frog   338 MGPGINGYDLNT----EPDRKSSSIAALRMKAKEHSAAMSWAT 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeobox	56..108	CDD:278475	39/51 (76%)
Drgx	NP_001097075.2	OAR	428..445	CDD:281777
alx4	XP_004913406.1	COG5576	120..266	CDD:227863	55/107 (51%)
		Homeobox	185..238	CDD:365835	40/52 (77%)
		OAR	352..370	CDD:367680	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920