Protein Alignment Drgx and uncx

DIOPT Version :10

• Sequence 1: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001305673.1
• Gene: uncx / 100492016
• XenbaseID: XB-GENE-920201
• Length: 483
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 124/512 - (24%)
• Similarity: 175/512 - (34%)
• Gaps: 163/512 - (31%)

  Fly    51 KQRRNRTTFTLQQLEELETAFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERL-K 114
            |:||.||.||..||||||.||.::||||||.||.||::::|.|:|||||||||||||||.|.. |
 Frog   100 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKK 164

  Fly   115 DEQRKRENGESSSSLDKLHDSRESSPDITGEIDDDMDDLPPRQR-SHSPLANGQMEQQHSHSHSH 178
            ...|...|...::...:..|..|.:       ..:::.:..::| ....:...|...||
 Frog   165 GPGRPAHNSHPTTCSGEPMDPEEIA-------RKELEKMEKKKRKQEKKMLRNQNRLQH------ 216

  Fly   179 SHSRSPGG-GMHLDSSDNERPLSSNQLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGG 242
                |||. .:|..|||::..|            ||:|.|.|..|..|.
 Frog   217 ----SPGDMSLHTPSSDSDSGL------------SQNLDSSSLESSHPD---------------- 249

  Fly   243 QGPSSPSNSRNTDSPIEVGGPMSLTTGSRMAASSNNSASSTPTPTTPHAPQMPHSSAAAAAAFGS 307
            .|.|......:.|...:........||.|...|...|    |.....::...|:...||......
 Frog   250 MGQSRSQTQASCDQTGQAFFQSQRNTGQRDRVSDKES----PVEANHNSGLCPNGRGAAFQKLNP 310

  Fly   308 HIFGNFGGGSNASDSNCGFRPVLSEQSAVAAAAAAAAAQRSANHPPLFLPPHLAAQFTHQPLFPG 372
                 |...|..|||                                  ||.......    |||
 Frog   311 -----FSVESLLSDS----------------------------------PPKRKTGIE----FPG 332

  Fly   373 LKGVSPFQSLCSCCSLKPPPPPGSSVVAPLS--IPVSSSSAASSPESPKSSGQGSVHDPRSNSVA 435
            |  .:|...:.....|..|      :..||.  :|.:|..:.|:.|.|....:.|:|:..|..
 Frog   333 L--TNPRTLIGKGHFLLYP------ITQPLGFIVPQASIKSNSAQELPSPGIKDSLHNSNSGQ-- 387

  Fly   436 ELRRKAQEHSAALLQSLHAAAAAGLAFPGLHLPPLSFAH-HPALGQHVVNHNNNNTMRMKHEAQD 499
                                       |.|:..|.|..: :|       |.:.|:|       |.
 Frog   388 ---------------------------PSLNTSPNSAQNLYP-------NKHTNST-------QS 411

  Fly   500 MTMNGLGPGSGSGSGSGSAGGGTSSAALLDLAESAVAYQQQQHATLSPPTTPTQQSS 556
            .|:......:|...|:.|:.|.|.:              :|..:|.|.|.:|....|
 Frog   412 TTLTVCKTENGDHHGATSSSGDTGT--------------EQLDSTYSEPKSPKSLKS 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	39/55 (71%)
		OAR	428..446	CDD:461067	1/17 (6%)
uncx	NP_001305673.1	homeobox domain	101..160		41/58 (71%)
		Homeodomain	102..158	CDD:459649	39/55 (71%)