DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34342 and FAR1

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_011518702.1	Gene:	FAR1 / 84188	HGNCID:	26222	Length:	518	Species:	Homo sapiens

Alignment Length:	487	Identity:	147/487 - (30%)
Similarity:	253/487 - (51%)	Gaps:	27/487 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSF-GLRKIYMLIRSKDNMSVQERLKGFFNESIFNRM 133
            :.::|....||:||.|||:||||.||||||. .:..:|:|:|.|...:.|||::...:..:|:|:
Human     4 IPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRL 68

  Fly   134 REESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTK 198
            |:|:|....|:..|.::.:...|.:...|:.::.....|:|:..|:|:|||.|.||:.:||:.|:
Human    69 RDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   199 KILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIG 263
            :::.|..:||:|:.|:|:||.|..||||.|.|.||...:..:|::......||..:..:...|||
Human   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIG 198

  Fly   264 QMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVR 328
            ..||||..||..||.:|......:...|.||.||.:::|:|||||.||..|||||...:.:|::|
Human   199 DRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   329 CIYGKASCKANMVPADYVVNAMIATAW--DIARRFKLRESKVDGKSELPVYNYVSDANN-ITWGQ 390
            .|....:..|::||.|.|||..:|.||  .:.|..:.|        .:.|||..:.:.| ..||:
Human   264 TIRASNNALADLVPVDVVVNMSLAAAWYSGVNRYMRPR--------NIMVYNCTTGSTNPFHWGE 320

  Fly   391 Y-MHLSRKGFHEPFDKALWCFSYVIIPSKPLHCAIAFFL---HNIPAYILDLIAMVTGQKRIYAK 451
            . .|:.......|.::|   |....:.....|....:::   |..||::.|:...:||:.....|
Human   321 VEYHVISTFKRNPLEQA---FRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMK 382

  Fly   452 AYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSGIRRY 516
            ...::.:.:..:.:|....|.:...|::.|...|..|::.....::..::|:||..:|..|.::|
Human   383 TITRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCLGTKKY 447

  Fly   517 FFKDSAND--------NKLQQRRTIYRRMLIL 540
            ...:..:.        |||:..|..:..:|::
Human   448 VLNEEMSGLPAARKHLNKLRNIRYGFNTILVI 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	142/456 (31%)
		FAR-N_SDR_e	78..397	CDD:187547	118/323 (37%)
		Sterile	429..519	CDD:281068	19/89 (21%)
FAR1	XP_011518702.1	PLN02996	2..449	CDD:215538	142/455 (31%)
		FAR-N_SDR_e	11..333	CDD:187547	118/329 (36%)
		Sterile	360..450	CDD:281068	19/89 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.950