DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34342 and MS2

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_187805.1	Gene:	MS2 / 820372	AraportID:	AT3G11980	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	147/567 - (25%)
Similarity:	246/567 - (43%)	Gaps:	115/567 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EEEQLFQEASSGTRTNSVDGIAA--PFTAA-----VSATPVTDFYSNATVLITGGTGFVGKVLTE 94
            :.|.|....:...||..::|:..  ||:.|     .....:..|......||||.|||:.|||.|
plant    84 DAETLVLSPNGNGRTIEINGVKTLMPFSGASMVGMKEGLGIISFLQGKKFLITGSTGFLAKVLIE 148

  Fly    95 KLLR-SFGLRKIYMLIRSKDNMSVQERLKG-FFNESIFNRMREESPQ-----LLAKVHPIRADY- 151
            |:|| :..:.|||:||::|...:..||||. ..:..:||.::|....     :|.|:.|:..:.
plant   149 KVLRMAPDVSKIYLLIKAKSKEAAIERLKNEVLDAELFNTLKETHGASYMSFMLTKLIPVTGNIC 213

  Fly   152 -SAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTKKILDLVMEMKHLKSFVH 215
             |.|.|..|||:.  ::.||.::.|..|:..|||:...|:|||..|...::....:.|.||.|:.
plant   214 DSNIGLQADSAEE--IAKEVDVIINSAANTTFNERYDVALDINTRGPGNLMGFAKKCKKLKLFLQ 276

  Fly   216 ISTLYCNCNRK-FIKEQVY--------ENEI-GYEKIMQIYR------------TFDDETLEKMR 258
            :||.|.|..|: .|.|:.:        ||.: |..|.:.:.|            |.:.:..:||:
plant   277 VSTAYVNGQRQGRIMEKPFSMGDCIATENFLEGNRKALDVDREMKLALEAARKGTQNQDEAQKMK 341

  Fly   259 HCLIGQ-----MPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTD--NLYGPS 316
            ...:.:     ..:||..||...|.::|.....:|..|.||.::.||||||||||.:  .:..|.
plant   342 DLGLERARSYGWQDTYVFTKAMGEMMINSTRGDVPVVIIRPSVIESTYKDPFPGWMEGNRMMDPI 406

  Fly   317 GLCTWSARGLVRCIYGKASCKA---------NMVPADYVVNAMIATAWDIARRFKLRESKVDGKS 372
            .||           |||.....         ::||||.||||.:|.   ||   |...:..|.:.
plant   407 VLC-----------YGKGQLTGFLVDPKGVLDVVPADMVVNATLAA---IA---KHGMAMSDPEP 454

  Fly   373 ELPVYNYVSDANN---------ITWGQYMH---LSRKGFHEPFDKALWCFSYVIIPSKPLHCAIA 425
            |:.||...|.|.|         :.:..|..   :..||  :|          :::....|..::.
plant   455 EINVYQIASSAINPLVFEDLAELLYNHYKTSPCMDSKG--DP----------IMVRLMKLFNSVD 507

  Fly   426 FFLHNIPAYILDLIAMVTGQKRIYAKAYGK--------------ISRIIDMMAWFGLKEWKFAHR 476
            .|..::.....:...:::|...:.:|...|              ::.|.:...::|   .:|.:.
plant   508 DFSDHLWRDAQERSGLMSGMSSVDSKMMQKLKFICKKSVEQAKHLATIYEPYTFYG---GRFDNS 569

  Fly   477 NIDELNELLPREERSVLQFNIATINWSEYFRS-YLSGIRRYFFKDSA 522
            |...|.|.:..:|:....|::.:|||::|..: ::.|:||:..|..|
plant   570 NTQRLMENMSEDEKREFGFDVGSINWTDYITNVHIPGLRRHVLKGRA 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	137/522 (26%)
		FAR-N_SDR_e	78..397	CDD:187547	113/377 (30%)
		Sterile	429..519	CDD:281068	18/104 (17%)
MS2	NP_187805.1	PLN02503	1..616	CDD:215279	146/565 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070