DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34342 and CG14893

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_650568.2	Gene:	CG14893 / 42023	FlyBaseID:	FBgn0038451	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	162/503 - (32%)
Similarity:	268/503 - (53%)	Gaps:	19/503 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSFGLRKIYMLIRSKDNMSVQERLKGFFNESIFNRMR 134
            :..||.:..|.:||.|||:|||:.|||||:..:::||.::|.|....:||||..:..:.:|..:.
  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRTTEVKRIYAMMRPKRGKDIQERLAIWQKDPLFEVLL 80

  Fly   135 EESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTKK 199
            :..|..|.::..|..|....||.|:.:||.:|.|||.||.:..|:|:|||.|..|:.||..||:.
  Fly    81 KAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTRL 145

  Fly   200 ILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYE--KIMQIYRTFDDETLEKMRHCLI 262
            :|.|..||..|::::||||.:.||....|:|:.|...:..:  .::.:.....::.::|:...|:
  Fly   146 MLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTCDANSVLAMSELLSEQMMDKLAPTLV 210

  Fly   263 GQMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLV 327
            |..|||||.||..||::|......:|..||||.::::|:::|..||.||||||.......:.|::
  Fly   211 GNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSHGVL 275

  Fly   328 RCIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGKSELPVYNYVSDANNITWG--- 389
            |.........|::||.||..||.:|:.|..::    .:|:.:..|:..:|.......|:...
  Fly   276 RLTTYDKDGYASLVPVDYCANAALASIWQTSK----DKSQRNAISQPAIYTLAPSEKNLLLNTDF 336

  Fly   390 -QYMHLSRKGFHEPFDKALWCFSYVIIPSKP-LHCAIAFFLHNIPAYILDLIAMVTGQKRIYAKA 452
             ::..:.|..|  |..|.:| :.:|...|.| :....|||.|.:|.|..||...::|:|....|.
  Fly   337 IKHSLIHRNDF--PLTKMIW-YPFVHNISNPRIFPLAAFFYHTLPGYFYDLALRLSGRKPRLVKL 398

  Fly   453 YGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSGIRRYF 517
            |..|...|.::..|....|.|..::.|.|..::..|:|.:..|::.|::|.||||..|.|:|.|.
  Fly   399 YRSIHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDWKEYFRKALFGMRLYL 463

  Fly   518 FKDSANDNKLQQRRTIYRRMLILH----TLLKTTFGLSLIMCMLRVYL 561
            .|:......|:|.|.::.|:.|||    |||....|. |:..::|:::
  Fly   464 TKEPPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGF-LLWTLVRLFI 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	148/455 (33%)
		FAR-N_SDR_e	78..397	CDD:187547	106/324 (33%)
		Sterile	429..519	CDD:281068	29/89 (33%)
CG14893	NP_650568.2	PLN02996	19..452	CDD:215538	141/439 (32%)
		FAR-N_SDR_e	23..339	CDD:187547	106/319 (33%)
		Sterile	375..465	CDD:281068	29/89 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466720
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	9.000