DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34342 and far1

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	506	Identity:	155/506 - (30%)
Similarity:	265/506 - (52%)	Gaps:	37/506 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSF-GLRKIYMLIRSKDNMSVQERLKGFFNESIFNRM 133
            :.::|....|||||.|||:||||.||||||. |::..|:|:|.|...:...|:....|..:|:|:
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly   134 REESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTK 198
            ||:.|....|:..|.:|.:..:||:.:.|:..|:..:.:||:..|:::|||.|.||:.:|||.|:
Zfish    69 REDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQ 133

  Fly   199 KILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIG 263
            |::.|...||||:.|:|:||.|.||:|:.|:|.||...:.|.|::......||:.:..|...|:|
Zfish   134 KMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRLLG 198

  Fly   264 QMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVR 328
            :.|||||.||..||.||.....::...|.||.||.:::|:|||||.||..||||:...:.:|::|
Zfish   199 ERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGILR 263

  Fly   329 CIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGKSELPVYNYVSDA-NNITWGQY- 391
            .:....:..|::||.|.|:|..:|.||....:...|      ...|.|||..:.. |...||:.
Zfish   264 TMRASNNAVADLVPVDVVINTTLAAAWYSGSQRHAR------PRSLLVYNCTTGGINPFHWGEVE 322

  Fly   392 MHLSRKGFHEPFDKALWCFSYVIIPSKPLHCAIAFFL---HNIPAYILDLIAMVTGQKRIYAKAY 453
            .|:.......|.::|   |....:.....|....:::   |..||::.||...::|::....|..
Zfish   323 YHVISTFKRNPLEQA---FRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREPRMMKTI 384

  Fly   454 GKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSGIRRYFF 518
            .::.:.:.::.:|....|.:...|:..|...:..|::.|..|::..::|:||..:|..|.::|..
Zfish   385 TRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTKKYVL 449

  Fly   519 KDSAND--------NKLQQRRTIYRRMLILHTLLKTTFGLSLIMCMLRVYL 561
            .:..:.        |||:.              ::.||...|::.:.|:::
Zfish   450 NEELSGLPAARKHLNKLRN--------------IRYTFNTVLVVLIWRIFI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	148/454 (33%)
		FAR-N_SDR_e	78..397	CDD:187547	123/321 (38%)
		Sterile	429..519	CDD:281068	20/89 (22%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	123/327 (38%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	20/89 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593273
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950