DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34342 and Far1

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001011933.1	Gene:	Far1 / 293173	RGDID:	1306647	Length:	515	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	150/501 - (29%)
Similarity:	254/501 - (50%)	Gaps:	58/501 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSF-GLRKIYMLIRSKDNMSVQERLKGFFNESIFNRM 133
            :.::|....:|:||.|||:||||.||||||. .:..:|:|:|.|...:.|||::...:..:|:|:
  Rat     4 IPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRL 68

  Fly   134 REESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTK 198
            |:|:|....|:..|.::.:...|.:...|:.::.....::|:..|:|:|||.|.||:.:||:.|:
  Rat    69 RDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   199 KILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIG 263
            :::.|..:||:|:.|:|:||.|..||||.|.|.||...:..:|::......||..:..:...|||
  Rat   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIG 198

  Fly   264 QMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVR 328
            ..||||..||..||.:|......:...|.||.||.:::|:|||||.||..|||||...:.:|::|
  Rat   199 DRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   329 CIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGKSELPVYNYVSDANN-ITWGQ-- 390
            .:....:..|::||.|.|||..:|.||         .|.|:....:.|||..:.:.| ..||:
  Rat   264 TMRASNNALADLVPVDVVVNTSLAAAW---------YSGVNRPRNIMVYNCTTGSTNPFHWGEVG 319

  Fly   391 -YMHLSRKGFHEPFDKALWCFSYVIIPSKPL-----HCAIAFF------------LHNIPAYILD 437
             |::.|.|                   :.||     |..:.|:            .|.:||.:||
  Rat   320 DYLNHSFK-------------------TNPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLD 365

  Fly   438 LIAMVTGQKRIYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINW 502
            |...:||||....|...::.:.:..:.:|....|.:...|::.|...|..|::.....::..::|
  Rat   366 LALRLTGQKPWMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHW 430

  Fly   503 SEYFRSYLSGIRRYFFKDSAND--------NKLQQRRTIYRRMLIL 540
            :||..:|..|.::|...:..:.        |||:..|..:..:|::
  Rat   431 AEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVI 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	145/470 (31%)
		FAR-N_SDR_e	78..397	CDD:187547	116/323 (36%)
		Sterile	429..519	CDD:281068	23/89 (26%)
Far1	NP_001011933.1	PLN02996	2..446	CDD:215538	145/469 (31%)
		FAR-N_SDR_e	11..330	CDD:187547	117/346 (34%)
		Sterile	371..447	CDD:281068	17/75 (23%)
		Necessary and sufficient for PEX19-mediated localization into peroxisome membrane. /evidence=ECO:0000250\|UniProtKB:Q8WVX9	451..507		5/26 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950