DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34342 and far1

DIOPT Version :9

Sequence 1:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	502	Identity:	155/502 - (30%)
Similarity:	266/502 - (52%)	Gaps:	29/502 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSF-GLRKIYMLIRSKDNMSVQERLKGFFNESIFNRM 133
            :.:||....|||||.|||:||||.||||||. .::.:|:|:|.|.:...:||:....:..:|:|:
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFDRL 68

  Fly   134 REESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTK 198
            |:|.|:...||..|.::.:..:||:...|:.||...:.|||:..|:|:|||.|.||:.:||:.|:
Frog    69 RDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIATR 133

  Fly   199 KILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIG 263
            ::|.|..::|.|:.|:|:||.|.|||||.|:|.||...:..:|:::.....||..:..:...|||
Frog   134 QLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPVDPKKLIESLEWMDDGLVNDITPKLIG 198

  Fly   264 QMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVR 328
            ..|||||.||..||.:|......:...|.||.||.:::|:|||||.||..|||||...:.:|::|
Frog   199 DRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   329 CIYGKASCKANMVPADYVVNAMIATAW--DIARRFKLRESKVDGKSELPVYNYVSDANN-ITWGQ 390
            .:....:..|:::|.|.|||..:|.||  .:.|..:.|        .:.|||..:...| ..||:
Frog   264 TMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRYSRPR--------NILVYNCTTGGTNPFHWGE 320

  Fly   391 Y-MHLSRKGFHEPFDKALWCFSYVIIPSKPLHCAIAFFL---HNIPAYILDLIAMVTGQKRIYAK 451
            . .|:.......|.::|   |....:.....|....:::   |..||::.|:...:||:.....|
Frog   321 VEYHVISTFKRNPLEQA---FRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDVYLRITGRSPRMMK 382

  Fly   452 AYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSGIRRY 516
            ...::.:.:.::.:|....|.:.:.|.:.|...|..:::....|::..::|:||..:|..|.::|
Frog   383 TITRLHKAMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCMGTKKY 447

  Fly   517 FFKDSANDNKLQQRRTIYRRMLILHTLLKTTFGLSLIMCML--RVYL 561
            ...:..:.....::.        |:.|....:|.:.|:.:|  ||::
Frog   448 VLNEEMSGLPAARKH--------LNKLRNIRYGFNTILVVLIWRVFI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	148/456 (32%)
		FAR-N_SDR_e	78..397	CDD:187547	123/323 (38%)
		Sterile	429..519	CDD:281068	19/89 (21%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020