Protein Alignment kmr and plekha6

DIOPT Version :9

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_021335504.1
• Gene: plekha6 / 568764
• ZFINID: ZDB-GENE-140106-14
• Length: 1230
• Species: Danio rerio
• Alignment Length: 1452
• Identity: 291/1452 - (20%)
• Similarity: 476/1452 - (32%)
• Gaps: 496/1452 - (34%)

  Fly   258 YAQQQQLQQQLHQQQQQQQQLQQQQ--QQHRHKN---------DLQTPGSEHGTVYIQQNHPNHV 311
            ::|.||||:   .|......:..||  |.|..:|         ||:..|...|         ...
Zfish    29 FSQPQQLQK---SQNDPNGTVGHQQVIQTHLEENGPLKALLSSDLEMNGKAGG---------RGP 81

  Fly   312 VNQACQ--------TQISAVKPKATPSSEESSSNSTKSPSHAPLDRKKSAGSIQALKSPITKRPP 368
            ||:|.:        :.:|.|.|..     ::.:..|::|..|....|:|..         .:|.|
Zfish    82 VNKASEANSNGNNLSMVSEVPPDG-----QNHTRGTRTPKRAATFGKRSNS---------MRRNP 132

  Fly   369 STPVTLSGWLHKQGSDGLKVWRKRWFVLAEYCLYYYKGPEEEKLLGSVLLPSYRVSACLPEDKIY 433
            :..|:..|||:||.|.|:|.|.||||||.:.||:|||..:||.:|||:.|.|:::......|.|.
Zfish   133 NAEVSRQGWLYKQASSGVKQWNKRWFVLTDRCLFYYKDEKEEGVLGSLPLLSFKIGPVQTSDSIT 197

  Fly   434 RKFAFK------------------------C---EHQNMRTYWLAADNSEAMMQWVRALAAASLM 471
            ||||||                        |   ||...|||:.:||:.:...:|::|::.|:.:
Zfish   198 RKFAFKVWCETEEEEEEEEESEDLKGSIAFCLQVEHAGTRTYYFSADSQKEQEEWIQAMSEAARV 262

  Fly   472 QAPSSGES------------------EPSVNSSLNHSGENSD---------SGIHTLQSHPGKGQ 509
            ..|::..|                  ||  .|...::|:..|         :|:.|..:.|.. .
Zfish   263 HIPTTPRSKSNPIPAADQNDMVAKRLEP--KSHAENNGQCPDLHEPVKHELNGLETRDTTPST-P 324

  Fly   510 PTPSSENTGSSGGGSGSGQPLYANAPPKPRRINDGGYSSPSPEHNEQQQQHPSRRLMSPTQQLYQ 574
            .||.:.||....|..|...|.:.|           |:.:..|                |....||
Zfish   325 VTPVTPNTDGRMGEKGGLGPHHPN-----------GWGNYGP----------------PNGSRYQ 362

  Fly   575 QQQHQRSQQQQQQQPQQHHAIYDTRTGHVSTALQLQQAQQQYSLDHLEAQFQQQQLDMEEQIARL 639
            .|::.|    ..::|...:.:  .|.|.|
Zfish   363 SQENVR----DMREPMDENVV--MRRGFV------------------------------------ 385

  Fly   640 QQQRAAEEIYGEREMYMAKLMQQRQGPNGTYPTQQQLLQAERRTPDAYGRSKQQRLFAAAAAAAD 704
              .|.|.|...:|:..|.:|             ||.:.|.....|...|||..:.........||
Zfish   386 --PRTAPERLAQRKSSMTQL-------------QQWVNQRRALVPQDDGRSPSRYYTVNRGMPAD 435

  Fly   705 YEDIYNMSQLAGGGGVPMSAQ----------EALLQEAASYRRPLSPPSYDGSKHVPAMPQRYTP 759
            |..:|        ||.|...:          |::...:|:|.|| ||              |:|.
Zfish   436 YYGVY--------GGAPYVDEYPLYPPGVRPESICSMSAAYNRP-SP--------------RWTV 477

  Fly   760 NHLEASAADQLINTMDLRARTAAAIVRPHSADFLEYEARAEAAAAAAAAAVAQSQQESGRAPRPK 824
            .....|..|   ..:..:.|....::.|.:.   .|..:.::|        ..|.:.....||.:
Zfish   478 EERRRSLRD---GPLYGQPRDPQWMMGPQAP---SYYPQLDSA--------QNSMRRLSIQPRSR 528

  Fly   825 SSLDINRTPDSFYYSEASYADKMRKSALYLQSGGAGAAQPQQPGSY----RTTGADFNSGVNTIG 885
            |   :.|:|.|                   .|||     |..|.|:    |:..|.|:.|...|.
Zfish   529 S---VPRSPSS-------------------SSGG-----PYSPHSFASPARSPSARFDRGPARIR 566

  Fly   886 YENPY--ERAYKRQELLAEAQGGGASSMPRMSRSASQGRSVASQLQSPQQEDLPPLNVHPGSIFP 948
            .|..|  ...|.    |..:........|...||.|||....:...||        ::|
Zfish   567 DEGIYADPSVYG----LRRSMSSPKYDFPGDRRSYSQGMYQYNYPASP--------SLH------ 613

  Fly   949 PSMSTQEIISKNEQFLRSASARLPKRSGGMDDDYSAGN---STTT------SPTGGAGASNSPQH 1004
                     ||.|..|   .|:|.:....:|...:.|:   |..|      ||.....:...|.|
Zfish   614 ---------SKMEDIL---DAQLQRNLEYLDQQMTDGDHLISMVTRMVERSSPRPKLFSQVPPFH 666

  Fly  1005 NLDG---------ERKREESMKRLLEWKQRMLQSPLTRKGIQQGGSNMSAMSKLGSNPNILLAST 1060
            ::.|         |.:..:.:.||.| :.|:|:.       |:...:...|.| .|...:|:|:.
Zfish   667 DVYGDLHPTLKLNEIETSKLLGRLCE-QNRLLKE-------QETVVHRLRMEK-DSLEGVLVATH 722

  Fly  1061 AVASGARYAP------QAGKTVLVG---NGNGTAQGAGNPPSASGIQRSRSESQAN--------- 1107
            ......|..|      |..|..|..   |..|....|.:..:.:.::....|...|
Zfish   723 QEMELYRNQPLVMEKLQLKKESLQNKLINIRGELSQASSALTTTRVEFEALEDDVNAIHGDLWEQ 787

  Fly  1108 VGPGG------------------VVYNNYSSDDEAGTVDDDNLYSATAGRSSSSKTTTKATTSQA 1154
            :..||                  |:...:.::...||  |...:...:|.|.|..|.:.|:...:
Zfish   788 LNAGGQSELVHRHIQKEFWRVQDVLEGLHKNNPSRGT--DTAKHRVASGASGSFSTNSPASPLSS 850

  Fly  1155 IVATTTAALAITNLGSSKNLETPNQTETEATPSSSSTASSTKAKFQLKPILKVHEASKTRIIQVQ 1219
             |:.|:.....:.:..|:...|.:....||.|.......|      .:|:    |:|::....|.
Zfish   851 -VSLTSPLSPFSPVPGSQPSPTKHLATEEAIPPRPPLPKS------YQPL----ESSQSFPPSVP 904

  Fly  1220 PKHLEERPKLRLQLPKAMG-----------------------NEEEQKQEDEEQEN---VEAEPV 1258
            |..|:.....|     :||                       |.:.:|..|.|.|.   .....|
Zfish   905 PLPLDSNAWQR-----SMGRNSGIHQEGYKDDGDFHSRKHNYNSQGEKTSDFETEQDRLSNQNKV 964

  Fly  1259 PILPKKTAPKSPQNANYVPVYNNKLVSNYENMEFGKPIPESKIPHSNAAITDPEET--PMLMQLK 1321
            .|:|.:|  |||....     ||.......|         .|:|:.:.:...|:..  |..::.|
Zfish   965 GIVPPRT--KSPSEEK-----NNSDAVQRRN---------GKVPNGHISRERPKSAVFPAEVKSK 1013

  Fly  1322 LFKEQQDQQKQQQENEEEDLTPTAESKPIPGEEDMGAPKVIKDQKLESN-EEEQELEDEDDSTAC 1385
            :..|:|:::.::.::..                       ::|::...| ...|.::....||:.
Zfish  1014 MSVEEQNERIRRNQSSS-----------------------VRDKRRSLNLSSNQHIDGFKSSTSY 1055

  Fly  1386 ----EEYTDDDID----EALAQDDEDEAVVEAVESQELAEERELQQIYVNEPITPTDQQFDESHY 1442
                ...|.|::|    ||..:.:..|:..|.:.......|.|...:.:::.::..|:......|
Zfish  1056 RVVRRRVTADEVDIKGLEAAVRGEGMESPREEIARLRRQVEPEHYDLDLSKELSMPDKVLIPERY 1120

  Fly  1443 LPMTP-------------KKVELGQPGVLTLVSATYAEE---------------EEENHYVEMTK 1479
            |.|.|             ||||    .:.||::.:..:.               |::.|  |..|
Zfish  1121 LDMEPNTPLSPEELREKQKKVE----RIKTLIAKSNLQNVVPVLDGPVEGPSNPEQQLH--EQEK 1179

  Fly  1480 GIQDEDCRSNYEIMCLASTSSS 1501
            .|         ||.|..:..:|
Zfish  1180 RI---------EISCALAAEAS 1192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	48/129 (37%)
		PH	372..469	CDD:278594	46/123 (37%)
plekha6	XP_021335504.1	PH_PEPP1_2_3	130..260	CDD:270068	48/129 (37%)
		SMC_N	<622..>775	CDD:330553	31/161 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12752
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100