Protein Alignment kmr and si:dkey-191m6.4

DIOPT Version :9

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_683216.5
• Gene: si:dkey-191m6.4 / 555573
• ZFINID: ZDB-GENE-121214-182
• Length: 696
• Species: Danio rerio
• Alignment Length: 964
• Identity: 168/964 - (17%)
• Similarity: 289/964 - (29%)
• Gaps: 351/964 - (36%)

  Fly   341 SPSHAPLDRKKSAGSIQALKSPITKRPPSTP----VTLSGWLHKQGSDGLKVWRKRWFVLAEYCL 401
            ||......|.:|...:....|..:.||.|..    |..:|||.||.|. :|.|:.|||||....|
Zfish     6 SPKIRQTRRARSKSMVMGEASRGSCRPTSPSLQEGVLKAGWLKKQRSI-MKNWQLRWFVLRADHL 69

  Fly   402 YYYKGPEEEKLLGSVLLPSYRVS--ACLPEDKIYRKFAF---------KCEHQNMRTYWLAADNS 455
            ::||..||.|..|.:.|...:|:  ...||:.....|..         ...|:   ::.|.|:..
Zfish    70 FFYKDEEETKPQGCISLKGSQVNELTANPEEPGRHLFEILPAGEKDKAAMSHE---SFLLMANTQ 131

  Fly   456 EAMMQWVRALAAASLMQAPSSGESEPSVNSSLNHSGENSDSGIHTLQSHPGKGQPTPSSENTGSS 520
            ..|..||:|:  ..::.||.
Zfish   132 SDMDDWVKAI--RRVIWAPF--------------------------------------------- 149

  Fly   521 GGGSGSGQPLYANAPPKPRRINDGGYSSPSPEHNEQQQQHPSRRLMSPTQQLYQQQQHQRSQQQQ 585
             ||...||           |:.|                         |.|
Zfish   150 -GGGIFGQ-----------RLED-------------------------TVQ-------------- 163

  Fly   586 QQQPQQHHAIYDTRTGHVSTALQLQQAQQQYSLDHLEAQFQQQQLDMEEQIARLQQQ----RAAE 646
                      |:.:.|.....|.::|.     :|.:    ::|.|| ||.:.|:..|    :..:
Zfish   164 ----------YERKFGPRLAPLLVEQC-----VDFI----REQGLD-EEGLFRMPGQANLVKELQ 208

  Fly   647 EIY--GEREMYMAKLMQQRQGPNGTYPTQQQLLQAE-RRTPDAYGRSKQQRLFAAAAAAADYEDI 708
            |.:  |::..:         ..|....|...||:.. |..|:            .......|||.
Zfish   209 EAFDCGDKPQF---------DSNTDVHTVASLLKLYLRELPE------------PVVPFCKYEDF 252

  Fly   709 YNMSQLAGG---------GGVPMSAQEA---LLQEAASYRRPLSPPSYDGSKHVPAMPQRYTPNH 761
            ...:||...         |.:.|:...|   ||:....:...:...|::....|..:...:.||.
Zfish   253 LTCAQLLTKDEEEGIQELGKLVMTLPAANFNLLKYICKFLDEVQSHSHENKMGVQNLATVFGPNM 317

  Fly   762 LEASAAD--QLINTMDLRARTAAAIVRPHSADFLEYEARAEAAAAAAAAAVAQSQQESGRAPRPK 824
            |.....|  .::....|.......::..|...:.|.::.         |:..|::.::.:..:|.
Zfish   318 LRPKMEDPVAIMEGTSLVQHLMTVLISEHDRLYTEKDSE---------ASQTQTEDQNQQQNQPS 373

  Fly   825 SSLDINRTPDSFYYSEASYADKMRKSALYLQSGGAGAAQPQQPGSYRTTGADFNSGVNTIGYENP 889
            :.:|        :.||..           |.:.|...|: ..|.|...:..|   ||:|
Zfish   374 TLVD--------WISEED-----------LNTTGPPTAK-NDPSSSSASSVD---GVST------ 409

  Fly   890 YERAYKRQELLAEAQGGGASSMPRMSRSASQGRSVASQLQSPQQEDLP--PLNVHPGSIFPPSMS 952
                                     |::..||:...:...|.|.:.||  ....:.||
Zfish   410 -------------------------SKTMPQGKGETAVSPSKQPKTLPGWKYTFNKGS------- 442

  Fly   953 TQEIISKNEQFLRSASARLPKRSGGMDDDYSAGNSTTTSPTGGAGASNSPQHNLDGERKREE-SM 1016
                         |...:..|.||...|..|:||..    ..|..:....:....|||.|:. |.
Zfish   443 -------------SPRPQSAKVSGSAVDVSSSGNWL----MNGLSSLRGHRRTSSGERSRDSGSS 490

  Fly  1017 KRLLEWKQRMLQSPLTRKGIQQGGSNMSAMSKLGSNPNILLASTAVASGARYAPQAGKTVLVGNG 1081
            :||..:                  .|:::.|.|||..::.....:.:|.....|.:|...|
Zfish   491 QRLSTY------------------DNVTSSSSLGSVLSMDSTPWSSSSCEISVPDSGSDPL---- 533

  Fly  1082 NGTAQGAGNPPSASGIQRSRSESQANVGPGGVVYNNYSSDDEAGTVDDDNLYSATAGRSSSSKTT 1146
             ||..|....||                    |....::|||..:...::  |:...|:|....:
Zfish   534 -GTEDGPQTEPS--------------------VLEERTTDDETKSTGQED--SSAEHRASGLFRS 575

  Fly  1147 TKATTSQAIVATTTAALAITNLGSSKNLETPNQTETEATPSSSSTASSTKAKFQLKPILKVHEAS 1211
            .....:..::....                        ..:..||:|......:||..|:..:.:
Zfish   576 DNGNAAAPLIRVVD------------------------EDADESTSSLVNVVAELKEELRAQKQT 616

  Fly  1212 -KTRIIQVQPK------HLE------ERPKLRLQLPKAMGNEEEQKQEDEEQEN 1252
             ::||.:::..      |:|      |:.:.|.::.:......|:.:||.|..|
Zfish   617 YESRIKKLEESNTALCAHMERLEQEMEQDRKRKRMLEIKLRNSERAREDAENRN 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	36/117 (31%)
		PH	372..469	CDD:278594	33/107 (31%)
si:dkey-191m6.4	XP_683216.5	PH-like	39..152	CDD:302622	36/164 (22%)
		PH	41..145	CDD:278594	33/109 (30%)
		RhoGAP_ARHGAP22_24_25	152..350	CDD:239855	44/288 (15%)
		GBP_C	<601..680	CDD:303769	14/70 (20%)
		coiled coil	651..662	CDD:293879	1/10 (10%)
		coiled coil	670..680	CDD:293879	1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910