DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kmr and dapp1

DIOPT Version :9

Sequence 1:	NP_001097775.2	Gene:	kmr / 5740131	FlyBaseID:	FBgn0085412	Length:	3090	Species:	Drosophila melanogaster
Sequence 2:	XP_031755425.1	Gene:	dapp1 / 548440	XenbaseID:	XB-GENE-482064	Length:	311	Species:	Xenopus tropicalis

Alignment Length:	175	Identity:	42/175 - (24%)
Similarity:	64/175 - (36%)	Gaps:	40/175 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 GSEHGTVYIQQNHPNHVVNQACQTQISAVKPKATPSSEESSSNSTKSPSHAPLDRKKSAGSIQAL 359
            |||.||: |...||                   .|.:.|..|.......|..:...:|...:
Frog   161 GSESGTL-ILLKHP-------------------YPCTVEEPSIYEAVRVHTAMQTGRSESDL--- 202

  Fly   360 KSPITKRPPSTPV--TLSGWLHKQGSDGLKVWRKRWFVLAEYCLYYYKGPEEEKLLGSVLLPSYR 422
                   .|..|.  |..|:|.|||. .:|.|:.|||:|:...|.|:|..     |.:..:.:..
Frog   203 -------VPVAPALGTKEGYLTKQGG-RVKSWKTRWFILSRNELKYFKDK-----LSTEPIKTLD 254

  Fly   423 VSAC--LPEDKIYRKFAFKCEHQNMRTYWLAADNSEAMMQWVRAL 465
            ::.|  :..|....|....|....:|||:|.|.......:|::.|
Frog   255 LTECSAVQFDYSQEKVNCFCMVFPLRTYYLCAKTGAEADEWIKML 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	29/104 (28%)
kmr	NP_001097775.2	PH	372..469	CDD:278594	27/98 (28%)
dapp1	XP_031755425.1	SH2_DAPP1_BAM32_like	73..164	CDD:198218	2/2 (100%)
dapp1	XP_031755425.1	PH_DAPP1	208..303	CDD:269977	27/98 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910