DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kmr and PLEK

DIOPT Version :9

Sequence 1:	NP_001097775.2	Gene:	kmr / 5740131	FlyBaseID:	FBgn0085412	Length:	3090	Species:	Drosophila melanogaster
Sequence 2:	NP_002655.2	Gene:	PLEK / 5341	HGNCID:	9070	Length:	350	Species:	Homo sapiens

Alignment Length:	94	Identity:	28/94 - (29%)
Similarity:	40/94 - (42%)	Gaps:	4/94 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   376 GWLHKQGSDGLKVWRKRWFVLAEYCLYYYKGPEEEKLLGSV-LLPSYRVSACLPEDKIYRKFAFK 439
            |:|.|:|| ....|:..|.||.|..:.:||...:....|.: |..|...|.|  :|...|.|.||
Human     9 GYLVKKGS-VFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPC--QDFGKRMFVFK 70

  Fly   440 CEHQNMRTYWLAADNSEAMMQWVRALAAA 468
            ......:.::..|...|....|||.:..|
Human    71 ITTTKQQDHFFQAAFLEERDAWVRDIKKA 99

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	28/94 (30%)
kmr	NP_001097775.2	PH	372..469	CDD:278594	28/94 (30%)
PLEK	NP_002655.2	PH1_Pleckstrin_2	3..110	CDD:270113	28/94 (30%)
		PH	6..101	CDD:278594	28/94 (30%)
		DEP_PLEK1	125..223	CDD:239892
		PH2_Pleckstrin_2	239..346	CDD:270114
		PH	245..347	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910