DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kmr and akt2

DIOPT Version :9

Sequence 1:	NP_001097775.2	Gene:	kmr / 5740131	FlyBaseID:	FBgn0085412	Length:	3090	Species:	Drosophila melanogaster
Sequence 2:	NP_937789.1	Gene:	akt2 / 378972	ZFINID:	ZDB-GENE-031007-5	Length:	479	Species:	Danio rerio

Alignment Length:	134	Identity:	35/134 - (26%)
Similarity:	60/134 - (44%)	Gaps:	12/134 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 VTLSGWLHKQGSDGLKVWRKRWFVL-AEYCLYYYKGPEEEKLLGSVLLPSYRVSAC---LPEDKI 432
            |...|||||:| :.:|.||.|:|:| ::.....||...|........|.::.|:.|   ..|...
Zfish     6 VVREGWLHKRG-EYIKTWRPRYFILKSDGSFIGYKEKPETSDANQPPLNNFSVAECQLMKTERPR 69

  Fly   433 YRKFAFKCEHQNM---RTYWLAADNSEAMMQWVRALAAASLMQAPSSGESEPSVNSSLNHSGENS 494
            ...|..:|.....   ||:.:  |::....:|:||:.|.:  ....|.|.:..::.:....|:||
Zfish    70 PNTFVIRCLQWTTVIERTFHV--DSNSEREEWIRAIQAVA--NGLKSREEDEPMDINFGSPGDNS 130

  Fly   495 DSGI 498
            ..|:
Zfish   131 LEGM 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	29/103 (28%)
kmr	NP_001097775.2	PH	372..469	CDD:278594	29/103 (28%)
akt2	NP_937789.1	PH_PKB	4..111	CDD:269947	29/109 (27%)
		PH	6..106	CDD:278594	28/102 (27%)
		S_TKc	150..407	CDD:214567
		STKc_PKB_beta	154..476	CDD:173686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910